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The role of animal models in evaluating reasonable safety and efficacy for human trials of cell-based interventions for neurologic conditions.
Regenberg A, Mathews DJ, Blass DM, Bok H, Coyle JT, Duggan P, Faden R, Finkel J, Gearhart JD, Hillis A, Hoke A, Johnson R, Johnston M, Kahn J, Kerr D, King P, Kurtzberg J, Liao SM, McDonald JW, McKhann G, Nelson KB, Rao M, Siegel AW, Smith K, Solter D, Song H, Sugarman J, Vescovi A, Young W, Greely HT, Traystman RJ. Regenberg A, et al. Among authors: young w. J Cereb Blood Flow Metab. 2009 Jan;29(1):1-9. doi: 10.1038/jcbfm.2008.98. Epub 2008 Aug 27. J Cereb Blood Flow Metab. 2009. PMID: 18728679 Free PMC article. Review.
Cell-based interventions for neurologic conditions: ethical challenges for early human trials.
Mathews DJ, Sugarman J, Bok H, Blass DM, Coyle JT, Duggan P, Finkel J, Greely HT, Hillis A, Hoke A, Johnson R, Johnston M, Kahn J, Kerr D, Kurtzberg J, Liao SM, McDonald JW, McKhann G, Nelson KB, Rao M, Regenberg A, Siegel AW, Smith K, Solter D, Song H, Vescovi A, Young W, Gearhart JD, Faden R. Mathews DJ, et al. Among authors: young w. Neurology. 2008 Jul 22;71(4):288-93. doi: 10.1212/01.wnl.0000316436.13659.80. Epub 2008 May 7. Neurology. 2008. PMID: 18463365 Review.
Unintended changes in cognition, mood, and behavior arising from cell-based interventions for neurological conditions: ethical challenges.
Duggan PS, Siegel AW, Blass DM, Bok H, Coyle JT, Faden R, Finkel J, Gearhart JD, Greely HT, Hillis A, Hoke A, Johnson R, Johnston M, Kahn J, Kerr D, King P, Kurtzberg J, Liao SM, McDonald JW, McKhann G, Nelson KB, Rao M, Regenberg A, Smith K, Solter D, Song H, Sugarman J, Traystman RJ, Vescovi A, Yanofski J, Young W, Mathews DJ. Duggan PS, et al. Among authors: young w. Am J Bioeth. 2009 May;9(5):31-6. doi: 10.1080/15265160902788645. Am J Bioeth. 2009. PMID: 19396681
Measurement of cigarette relighting: A common but understudied behavior.
Young WJ, Kennedy M, Wackowski OA, Mitarotondo A, Assan MA, Scalia D, Stepanov I, Steinberg MB, Heckman CJ. Young WJ, et al. Drug Alcohol Depend. 2024 Mar 6;257:111257. doi: 10.1016/j.drugalcdep.2024.111257. Online ahead of print. Drug Alcohol Depend. 2024. PMID: 38493565 Free article.
T-wave morphology abnormalities in the STREAM stage 1 trial.
Hughes G, Young WJ, Bern H, Crook A, Lambiase PD, Goodall RL, Nunn AJ, Meredith SK. Hughes G, et al. Among authors: young wj. Expert Opin Drug Saf. 2024 Mar 10:1-8. doi: 10.1080/14740338.2024.2322116. Online ahead of print. Expert Opin Drug Saf. 2024. PMID: 38462751
Empowering Voices: Inspiring Women in Medicinal Chemistry.
Blanco MJ, Bronson JJ, DiMauro EF, Dzierba C, Eggen M, Garner AL, Georg G, Giarolla J, Goodwin NC, Grenier-Davies MC, Haskell-Luevano C, Holzgrabe U, Huang R, Lagiakos HR, Leftheris K, Martin Y, Matos MJ, May-Dracka TL, Müller CE, Newman AH, Parmee E, Petter JC, Tamayo NA, Wexler RR, Bolognesi ML, Ripka A, Young W. Blanco MJ, et al. Among authors: young w. J Med Chem. 2024 Mar 28;67(6):4251-4258. doi: 10.1021/acs.jmedchem.4c00493. Epub 2024 Mar 8. J Med Chem. 2024. PMID: 38456628
2,672 results