Yu C - Search Results

1

Coadministration of UCN-01 with MEK1/2 inhibitors potently induces apoptosis in BCR/ABL+ leukemia cells sensitive and resistant to ST1571.

Yu C, Dai Y, Dent P, Grant S. Yu C, et al. Cancer Biol Ther. 2002 Nov-Dec;1(6):674-82. doi: 10.4161/cbt.319. Cancer Biol Ther. 2002. PMID: 12642693

2

HER receptor signaling confers resistance to the insulin-like growth factor-I receptor inhibitor, BMS-536924.

Haluska P, Carboni JM, TenEyck C, Attar RM, Hou X, Yu C, Sagar M, Wong TW, Gottardis MM, Erlichman C. Haluska P, et al. Among authors: yu c. Mol Cancer Ther. 2008 Sep;7(9):2589-98. doi: 10.1158/1535-7163.MCT-08-0493. Epub 2008 Sep 2. Mol Cancer Ther. 2008. PMID: 18765823 Free PMC article.

3

BRAF V600E disrupts AZD6244-induced abrogation of negative feedback pathways between extracellular signal-regulated kinase and Raf proteins.

Friday BB, Yu C, Dy GK, Smith PD, Wang L, Thibodeau SN, Adjei AA. Friday BB, et al. Among authors: yu c. Cancer Res. 2008 Aug 1;68(15):6145-53. doi: 10.1158/0008-5472.CAN-08-1430. Cancer Res. 2008. PMID: 18676837

4

Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.

Meng XW, Lee SH, Dai H, Loegering D, Yu C, Flatten K, Schneider P, Dai NT, Kumar SK, Smith BD, Karp JE, Adjei AA, Kaufmann SH. Meng XW, et al. Among authors: yu c. J Biol Chem. 2007 Oct 12;282(41):29831-46. doi: 10.1074/jbc.M706110200. Epub 2007 Aug 13. J Biol Chem. 2007. PMID: 17698840

5

Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways.

Yu C, Friday BB, Lai JP, Yang L, Sarkaria J, Kay NE, Carter CA, Roberts LR, Kaufmann SH, Adjei AA. Yu C, et al. Mol Cancer Ther. 2006 Sep;5(9):2378-87. doi: 10.1158/1535-7163.MCT-06-0235. Mol Cancer Ther. 2006. PMID: 16985072

6

The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006.

Yu C, Bruzek LM, Meng XW, Gores GJ, Carter CA, Kaufmann SH, Adjei AA. Yu C, et al. Oncogene. 2005 Oct 20;24(46):6861-9. doi: 10.1038/sj.onc.1208841. Oncogene. 2005. PMID: 16007148

7

Apigenin sensitizes colon cancer cells to antitumor activity of ABT-263.

Shao H, Jing K, Mahmoud E, Huang H, Fang X, Yu C. Shao H, et al. Among authors: yu c. Mol Cancer Ther. 2013 Dec;12(12):2640-50. doi: 10.1158/1535-7163.MCT-13-0066. Epub 2013 Oct 14. Mol Cancer Ther. 2013. PMID: 24126433 Free PMC article.

8

Abrogation of MAPK and Akt signaling by AEE788 synergistically potentiates histone deacetylase inhibitor-induced apoptosis through reactive oxygen species generation.

Yu C, Friday BB, Lai JP, McCollum A, Atadja P, Roberts LR, Adjei AA. Yu C, et al. Clin Cancer Res. 2007 Feb 15;13(4):1140-8. doi: 10.1158/1078-0432.CCR-06-1751. Clin Cancer Res. 2007. PMID: 17317822

9

Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways.

Hahn M, Li W, Yu C, Rahmani M, Dent P, Grant S. Hahn M, et al. Among authors: yu c. Mol Cancer Ther. 2005 Mar;4(3):457-70. doi: 10.1158/1535-7163.MCT-04-0137. Mol Cancer Ther. 2005. PMID: 15767555

10

The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib.

Yu C, Rahmani M, Dent P, Grant S. Yu C, et al. Exp Cell Res. 2004 May 1;295(2):555-66. doi: 10.1016/j.yexcr.2004.02.001. Exp Cell Res. 2004. PMID: 15093752

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