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JAK-STAT6 Pathway Inhibitors Block Eotaxin-3 Secretion by Epithelial Cells and Fibroblasts from Esophageal Eosinophilia Patients: Promising Agents to Improve Inflammation and Prevent Fibrosis in EoE.
Cheng E, Zhang X, Wilson KS, Wang DH, Park JY, Huo X, Yu C, Zhang Q, Spechler SJ, Souza RF. Cheng E, et al. Among authors: yu c. PLoS One. 2016 Jun 16;11(6):e0157376. doi: 10.1371/journal.pone.0157376. eCollection 2016. PLoS One. 2016. PMID: 27310888 Free PMC article.
Hypoxia-inducible factor-2α plays a role in mediating oesophagitis in GORD.
Huo X, Agoston AT, Dunbar KB, Cipher DJ, Zhang X, Yu C, Cheng E, Zhang Q, Pham TH, Tambar UK, Bruick RK, Wang DH, Odze RD, Spechler SJ, Souza RF. Huo X, et al. Among authors: yu c. Gut. 2017 Sep;66(9):1542-1554. doi: 10.1136/gutjnl-2016-312595. Epub 2016 Sep 30. Gut. 2017. PMID: 27694141 Free PMC article. Clinical Trial.
Deoxycholic acid causes DNA damage while inducing apoptotic resistance through NF-κB activation in benign Barrett's epithelial cells.
Huo X, Juergens S, Zhang X, Rezaei D, Yu C, Strauch ED, Wang JY, Cheng E, Meyer F, Wang DH, Zhang Q, Spechler SJ, Souza RF. Huo X, et al. Among authors: yu c. Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G278-86. doi: 10.1152/ajpgi.00092.2011. Epub 2011 Jun 2. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21636532 Free PMC article.
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