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Peroxisomes can oxidize medium- and long-chain fatty acids through a pathway involving ABCD3 and HSD17B4.
Violante S, Achetib N, van Roermund CWT, Hagen J, Dodatko T, Vaz FM, Waterham HR, Chen H, Baes M, Yu C, Argmann CA, Houten SM. Violante S, et al. Among authors: yu c. FASEB J. 2019 Mar;33(3):4355-4364. doi: 10.1096/fj.201801498R. Epub 2018 Dec 12. FASEB J. 2019. PMID: 30540494 Free PMC article.
We summarize that peroxisomal FAO is important when mitochondrial FAO is defective or overloaded.-Violante, S., Achetib, N., van Roermund, C. W. T., Hagen, J., Dodatko, T., Vaz, F. M., Waterham, H. R., Chen, H., Baes, M., Yu, C., Argmann, C. ...
We summarize that peroxisomal FAO is important when mitochondrial FAO is defective or overloaded.-Violante, S., Achetib, N., van Roermund, …
Mild inborn errors of metabolism in commonly used inbred mouse strains.
Leandro J, Violante S, Argmann CA, Hagen J, Dodatko T, Bender A, Zhang W, Williams EG, Bachmann AM, Auwerx J, Yu C, Houten SM. Leandro J, et al. Among authors: yu c. Mol Genet Metab. 2019 Apr;126(4):388-396. doi: 10.1016/j.ymgme.2019.01.021. Epub 2019 Jan 24. Mol Genet Metab. 2019. PMID: 30709776 Free PMC article.
Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex.
Leandro J, Khamrui S, Wang H, Suebsuwong C, Nemeria NS, Huynh K, Moustakim M, Secor C, Wang M, Dodatko T, Stauffer B, Wilson CG, Yu C, Arkin MR, Jordan F, Sanchez R, DeVita RJ, Lazarus MB, Houten SM. Leandro J, et al. Among authors: yu c. ACS Chem Biol. 2020 Aug 21;15(8):2041-2047. doi: 10.1021/acschembio.0c00114. Epub 2020 Jul 9. ACS Chem Biol. 2020. PMID: 32633484 Free PMC article.
Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis.
Ranea-Robles P, Violante S, Argmann C, Dodatko T, Bhattacharya D, Chen H, Yu C, Friedman SL, Puchowicz M, Houten SM. Ranea-Robles P, et al. Among authors: yu c. Cell Mol Life Sci. 2021 Jul;78(14):5631-5646. doi: 10.1007/s00018-021-03869-9. Epub 2021 Jun 10. Cell Mol Life Sci. 2021. PMID: 34110423 Free PMC article.
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