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PGC7 promotes tumor oncogenic dedifferentiation through remodeling DNA methylation pattern for key developmental transcription factors.
Yan Q, Zhang Y, Fang X, Liu B, Wong TL, Gong L, Liu S, Yu D, Liu M, Jiang L, Wang X, Wei T, Jia Y, Li L, Sun L, Tang Y, Zhou N, Yuan YF, Li Y, Ma S, Guan XY. Yan Q, et al. Among authors: yu d. Cell Death Differ. 2021 Jun;28(6):1955-1970. doi: 10.1038/s41418-020-00726-3. Epub 2021 Jan 26. Cell Death Differ. 2021. PMID: 33500560 Free PMC article.
Elevated expression of RIT1 hyperactivates RAS/MAPK signal and sensitizes hepatocellular carcinoma to combined treatment with sorafenib and AKT inhibitor.
Sun L, Xi S, Zhou Z, Zhang F, Hu P, Cui Y, Wu S, Wang Y, Wu S, Wang Y, Du Y, Zheng J, Yang H, Chen M, Yan Q, Yu D, Shi C, Zhang Y, Xie D, Guan XY, Li Y. Sun L, et al. Among authors: yu d. Oncogene. 2022 Jan;41(5):732-744. doi: 10.1038/s41388-021-02130-8. Epub 2021 Nov 29. Oncogene. 2022. PMID: 34845378
Foxd3 suppresses interleukin-10 expression in B cells.
Zhang Y, Wang Z, Xiao H, Liu X, Zhu G, Yu D, Han G, Chen G, Hou C, Ma N, Shen B, Li Y, Wang T, Wang R. Zhang Y, et al. Among authors: yu d. Immunology. 2017 Apr;150(4):478-488. doi: 10.1111/imm.12701. Epub 2017 Jan 12. Immunology. 2017. PMID: 27995618 Free PMC article.
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