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Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.
Niu G, Wright KL, Huang M, Song L, Haura E, Turkson J, Zhang S, Wang T, Sinibaldi D, Coppola D, Heller R, Ellis LM, Karras J, Bromberg J, Pardoll D, Jove R, Yu H. Niu G, et al. Among authors: yu h. Oncogene. 2002 Mar 27;21(13):2000-8. doi: 10.1038/sj.onc.1205260. Oncogene. 2002. PMID: 11960372
A critical role for Stat3 signaling in immune tolerance.
Cheng F, Wang HW, Cuenca A, Huang M, Ghansah T, Brayer J, Kerr WG, Takeda K, Akira S, Schoenberger SP, Yu H, Jove R, Sotomayor EM. Cheng F, et al. Among authors: yu h. Immunity. 2003 Sep;19(3):425-36. doi: 10.1016/s1074-7613(03)00232-2. Immunity. 2003. PMID: 14499117
Targeting STAT3 affects melanoma on multiple fronts.
Kortylewski M, Jove R, Yu H. Kortylewski M, et al. Among authors: yu h. Cancer Metastasis Rev. 2005 Jun;24(2):315-27. doi: 10.1007/s10555-005-1580-1. Cancer Metastasis Rev. 2005. PMID: 15986140 Review.
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