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16,985 results
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A rational chemical intervention strategy to circumvent bioactivation liabilities associated with a nonpeptidyl thrombopoietin receptor agonist containing a 2-amino-4-arylthiazole motif.
Kalgutkar AS, Driscoll J, Zhao SX, Walker GS, Shepard RM, Soglia JR, Atherton J, Yu L, Mutlib AE, Munchhof MJ, Reiter LA, Jones CS, Doty JL, Trevena KA, Shaffer CL, Ripp SL. Kalgutkar AS, et al. Among authors: yu l. Chem Res Toxicol. 2007 Dec;20(12):1954-65. doi: 10.1021/tx700270r. Epub 2007 Oct 13. Chem Res Toxicol. 2007. PMID: 17935300
Characterization of HKI-272 covalent binding to human serum albumin.
Wang J, Li-Chan XX, Atherton J, Deng L, Espina R, Yu L, Horwatt P, Ross S, Lockhead S, Ahmad S, Chandrasekaran A, Oganesian A, Scatina J, Mutlib A, Talaat R. Wang J, et al. Among authors: yu l. Drug Metab Dispos. 2010 Jul;38(7):1083-93. doi: 10.1124/dmd.110.032292. Epub 2010 Apr 16. Drug Metab Dispos. 2010. PMID: 20400660
Obtaining exposures of metabolites in preclinical species through plasma pooling and quantitative NMR: addressing metabolites in safety testing (MIST) guidance without using radiolabeled compounds and chemically synthesized metabolite standards.
Vishwanathan K, Babalola K, Wang J, Espina R, Yu L, Adedoyin A, Talaat R, Mutlib A, Scatina J. Vishwanathan K, et al. Among authors: yu l. Chem Res Toxicol. 2009 Feb;22(2):311-22. doi: 10.1021/tx8003328. Chem Res Toxicol. 2009. PMID: 19067650
Expert consensus on the diagnosis and treatment of myofascial pain syndrome.
Cao QW, Peng BG, Wang L, Huang YQ, Jia DL, Jiang H, Lv Y, Liu XG, Liu RG, Li Y, Song T, Shen W, Yu LZ, Zheng YJ, Liu YQ, Huang D. Cao QW, et al. Among authors: yu lz. World J Clin Cases. 2021 Mar 26;9(9):2077-2089. doi: 10.12998/wjcc.v9.i9.2077. World J Clin Cases. 2021. PMID: 33850927 Free PMC article. Review.
Application of network link prediction in drug discovery.
Abbas K, Abbasi A, Dong S, Niu L, Yu L, Chen B, Cai SM, Hasan Q. Abbas K, et al. Among authors: yu l. BMC Bioinformatics. 2021 Apr 12;22(1):187. doi: 10.1186/s12859-021-04082-y. BMC Bioinformatics. 2021. PMID: 33845763
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