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Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.
Shen M, Wei Y, Kim H, Wan L, Jiang YZ, Hang X, Raba M, Remiszewski S, Rowicki M, Wu CG, Wu S, Zhang L, Lu X, Yuan M, Smith HA, Zheng A, Bertino J, Jin JF, Xing Y, Shao ZM, Kang Y. Shen M, et al. Among authors: yuan m. Nat Cancer. 2022 Jan;3(1):43-59. doi: 10.1038/s43018-021-00279-5. Epub 2021 Nov 29. Nat Cancer. 2022. PMID: 35121987 Free PMC article.
MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors.
Wan L, Lu X, Yuan S, Wei Y, Guo F, Shen M, Yuan M, Chakrabarti R, Hua Y, Smith HA, Blanco MA, Chekmareva M, Wu H, Bronson RT, Haffty BG, Xing Y, Kang Y. Wan L, et al. Among authors: yuan s, yuan m. Cancer Cell. 2014 Jul 14;26(1):92-105. doi: 10.1016/j.ccr.2014.04.027. Epub 2014 Jun 26. Cancer Cell. 2014. PMID: 24981741 Free PMC article.
Tumor-derived Jagged1 promotes cancer progression through immune evasion.
Meng J, Jiang YZ, Zhao S, Tao Y, Zhang T, Wang X, Zhang Y, Sun K, Yuan M, Chen J, Wei Y, Lan X, Chen M, David CJ, Chang Z, Guo X, Pan D, Chen M, Shao ZM, Kang Y, Zheng H. Meng J, et al. Among authors: yuan m. Cell Rep. 2022 Mar 8;38(10):110492. doi: 10.1016/j.celrep.2022.110492. Cell Rep. 2022. PMID: 35263601 Free article.
Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy.
Zheng H, Bae Y, Kasimir-Bauer S, Tang R, Chen J, Ren G, Yuan M, Esposito M, Li W, Wei Y, Shen M, Zhang L, Tupitsyn N, Pantel K, King C, Sun J, Moriguchi J, Jun HT, Coxon A, Lee B, Kang Y. Zheng H, et al. Among authors: yuan m. Cancer Cell. 2017 Dec 11;32(6):731-747.e6. doi: 10.1016/j.ccell.2017.11.002. Cancer Cell. 2017. PMID: 29232552 Free PMC article.
4,838 results