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A systemic route for drug loading to lymphatic phagocytes.
Papisov MI, Yurkovetskiy A, Syed S, Koshkina N, Yin M, Hiller A, Fischman AJ. Papisov MI, et al. Mol Pharm. 2005 Jan-Feb;2(1):47-56. doi: 10.1021/mp0499149. Mol Pharm. 2005. PMID: 15804177 Free PMC article.
Fully degradable hydrophilic polyals for protein modification.
Yurkovetskiy A, Choi S, Hiller A, Yin M, McCusker C, Syed S, Fischman AJ, Papisov MI. Yurkovetskiy A, et al. Biomacromolecules. 2005 Sep-Oct;6(5):2648-58. doi: 10.1021/bm049210k. Biomacromolecules. 2005. PMID: 16153103 Free PMC article.
Semisynthetic hydrophilic polyals.
Papisov MI, Hiller A, Yurkovetskiy A, Yin M, Barzana M, Hillier S, Fischman AJ. Papisov MI, et al. Biomacromolecules. 2005 Sep-Oct;6(5):2659-70. doi: 10.1021/bm0502157. Biomacromolecules. 2005. PMID: 16153104 Free PMC article.
Development of a Novel DNA Mono-alkylator Platform for Antibody-Drug Conjugates.
Thomas JD, Yurkovetskiy AV, Yin M, Bodyak ND, Tang S, Protopopova M, Kelleher E, Jones B, Yang L, Custar D, Catcott KC, Demady DR, Collins SD, Xu L, Bu C, Qin L, Ter-Ovanesyan E, Damelin M, Toader D, Lowinger TB. Thomas JD, et al. Among authors: yurkovetskiy av. Mol Cancer Ther. 2024 Apr 2;23(4):541-551. doi: 10.1158/1535-7163.MCT-23-0622. Mol Cancer Ther. 2024. PMID: 38354416
Discovery and Preclinical Characterization of XMT-1660, an Optimized B7-H4-Targeted Antibody-Drug Conjugate for the Treatment of Cancer.
Toader D, Fessler SP, Collins SD, Conlon PR, Bollu R, Catcott KC, Chin CN, Dirksen A, Du B, Duvall JR, Higgins S, Kozytska MV, Bellovoda K, Faircloth C, Lee D, Li F, Qin L, Routhier C, Shaw P, Stevenson CA, Wang J, Wongthida P, Ter-Ovanesyan E, Ditty E, Bradley SP, Xu L, Yin M, Yurkovetskiy AV, Mosher R, Damelin M, Lowinger TB. Toader D, et al. Among authors: yurkovetskiy av. Mol Cancer Ther. 2023 Sep 5;22(9):999-1012. doi: 10.1158/1535-7163.MCT-22-0786. Mol Cancer Ther. 2023. PMID: 37294948 Free PMC article. Clinical Trial.
Discovery of novel polyamide-pyrrolobenzodiazepine hybrids for antibody-drug conjugates.
Thomas JD, Yurkovetskiy AV, Yin M, Bodyak ND, Gumerov DR, Tang S, Kelleher E, Jones BD, Protopopova M, Qin L, Uttard A, Demady DR, Lowinger TB. Thomas JD, et al. Among authors: yurkovetskiy av. Bioorg Med Chem Lett. 2022 Sep 15;72:128876. doi: 10.1016/j.bmcl.2022.128876. Epub 2022 Jul 3. Bioorg Med Chem Lett. 2022. PMID: 35788036
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