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Page 1
Proposed Diagnostic Criteria and Classification of Canine Mast Cell Neoplasms: A Consensus Proposal.
Willmann M, Yuzbasiyan-Gurkan V, Marconato L, Dacasto M, Hadzijusufovic E, Hermine O, Sadovnik I, Gamperl S, Schneeweiss-Gleixner M, Gleixner KV, Böhm T, Peter B, Eisenwort G, Moriggl R, Li Z, Jawhar M, Sotlar K, Jensen-Jarolim E, Sexl V, Horny HP, Galli SJ, Arock M, Vail DM, Kiupel M, Valent P. Willmann M, et al. Among authors: yuzbasiyan gurkan v. Front Vet Sci. 2021 Dec 10;8:755258. doi: 10.3389/fvets.2021.755258. eCollection 2021. Front Vet Sci. 2021. PMID: 34957277 Free PMC article. Review.
The proposed classification includes cutaneous mast cell tumors and their sub-variants defined by grading- and staging results, mucosal mast cell tumors, extracutaneous/extramucosal mast cell tumors without skin involvement, and mast …
The proposed classification includes cutaneous mast cell tumors and their sub-variants defined by grading- and staging results …
NI-1: a novel canine mastocytoma model for studying drug resistance and IgER-dependent mast cell activation.
Hadzijusufovic E, Peter B, Herrmann H, Rülicke T, Cerny-Reiterer S, Schuch K, Kenner L, Thaiwong T, Yuzbasiyan-Gurkan V, Pickl WF, Willmann M, Valent P. Hadzijusufovic E, et al. Among authors: yuzbasiyan gurkan v. Allergy. 2012 Jul;67(7):858-68. doi: 10.1111/j.1398-9995.2012.02833.x. Epub 2012 May 15. Allergy. 2012. PMID: 22583069 Free PMC article.
BACKGROUND: Advanced mast cell (MC) disorders are characterized by uncontrolled growth of neoplastic MC in various organs, mediator-related symptoms, and a poor prognosis. ...NI-1 cells expressed several MC differentiation antigens, including tryptase, Kit, a …
BACKGROUND: Advanced mast cell (MC) disorders are characterized by uncontrolled growth of neoplastic MC in various organs, med …
Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11.
Gregory-Bryson E, Bartlett E, Kiupel M, Hayes S, Yuzbasiyan-Gurkan V. Gregory-Bryson E, et al. Among authors: yuzbasiyan gurkan v. BMC Cancer. 2010 Oct 15;10:559. doi: 10.1186/1471-2407-10-559. BMC Cancer. 2010. PMID: 20950418 Free PMC article.
CONCLUSIONS: The deletion mutations detected in canine GISTs are similar to those previously found in the juxtamembrane domain of c-KIT in canine cutaneous mast cell tumors in our laboratory as well as to those reported in human GISTs. Interestingly, none of the oth …
CONCLUSIONS: The deletion mutations detected in canine GISTs are similar to those previously found in the juxtamembrane domain of c-KIT in c …
KIT polymorphisms and mutations determine responses of neoplastic mast cells to bafetinib (INNO-406).
Peter B, Hadzijusufovic E, Blatt K, Gleixner KV, Pickl WF, Thaiwong T, Yuzbasiyan-Gurkan V, Willmann M, Valent P. Peter B, et al. Among authors: yuzbasiyan gurkan v. Exp Hematol. 2010 Sep;38(9):782-91. doi: 10.1016/j.exphem.2010.05.004. Epub 2010 May 26. Exp Hematol. 2010. PMID: 20685234 Free article.
OBJECTIVE: Advanced systemic mastocytosis (SM) is characterized by uncontrolled growth of neoplastic mast cells (MC) and drug resistance. The tyrosine kinase receptor KIT is often mutated and activated and thus contributes to malignant growth of MC. ...MATERIALS AND …
OBJECTIVE: Advanced systemic mastocytosis (SM) is characterized by uncontrolled growth of neoplastic mast cells (MC) and drug …
H1-receptor antagonists terfenadine and loratadine inhibit spontaneous growth of neoplastic mast cells.
Hadzijusufovic E, Peter B, Gleixner KV, Schuch K, Pickl WF, Thaiwong T, Yuzbasiyan-Gurkan V, Mirkina I, Willmann M, Valent P. Hadzijusufovic E, et al. Among authors: yuzbasiyan gurkan v. Exp Hematol. 2010 Oct;38(10):896-907. doi: 10.1016/j.exphem.2010.05.008. Epub 2010 Jun 1. Exp Hematol. 2010. PMID: 20570632 Free PMC article.
OBJECTIVE: In mast cell (MC) neoplasms, clinical problems requiring therapy include local aggressive and sometimes devastating growth of MCs and mediator-related symptoms. ...RESULTS: We found that the HR1 antagonists terfenadine and loratadine suppress spontaneous …
OBJECTIVE: In mast cell (MC) neoplasms, clinical problems requiring therapy include local aggressive and sometimes devastating …
Growth-inhibitory effects of four tyrosine kinase inhibitors on neoplastic feline mast cells exhibiting a Kit exon 8 ITD mutation.
Hadzijusufovic E, Peter B, Rebuzzi L, Baumgartner C, Gleixner KV, Gruze A, Thaiwong T, Pickl WF, Yuzbasiyan-Gurkan V, Willmann M, Valent P. Hadzijusufovic E, et al. Among authors: yuzbasiyan gurkan v. Vet Immunol Immunopathol. 2009 Dec 15;132(2-4):243-50. doi: 10.1016/j.vetimm.2009.05.007. Epub 2009 May 18. Vet Immunol Immunopathol. 2009. PMID: 19505729 Free PMC article.
Systemic mastocytosis (SM) in felines is a rare neoplasm defined by increased growth and accumulation of immature mast cells (MC) in various organs including the spleen. Although in many cases splenectomy is an effective approach, relapses may occur. ...
Systemic mastocytosis (SM) in felines is a rare neoplasm defined by increased growth and accumulation of immature mast cells ( …
Evaluation of prognostic markers for canine mast cell tumors treated with vinblastine and prednisone.
Webster JD, Yuzbasiyan-Gurkan V, Thamm DH, Hamilton E, Kiupel M. Webster JD, et al. Among authors: yuzbasiyan gurkan v. BMC Vet Res. 2008 Aug 13;4:32. doi: 10.1186/1746-6148-4-32. BMC Vet Res. 2008. PMID: 18700956 Free PMC article.
BACKGROUND: Canine cutaneous mast cell tumor (MCT) is a common neoplastic disease associated with a variable biologic behavior. ...
BACKGROUND: Canine cutaneous mast cell tumor (MCT) is a common neoplastic disease associated with a variable biologic behavior …
Synergistic antiproliferative effects of KIT tyrosine kinase inhibitors on neoplastic canine mast cells.
Gleixner KV, Rebuzzi L, Mayerhofer M, Gruze A, Hadzijusufovic E, Sonneck K, Vales A, Kneidinger M, Samorapoompichit P, Thaiwong T, Pickl WF, Yuzbasiyan-Gurkan V, Sillaber C, Willmann M, Valent P. Gleixner KV, et al. Among authors: yuzbasiyan gurkan v. Exp Hematol. 2007 Oct;35(10):1510-21. doi: 10.1016/j.exphem.2007.06.005. Epub 2007 Aug 2. Exp Hematol. 2007. PMID: 17681669 Free article.
Aggressive mast cell (MC) tumors are hematopoietic neoplasms characterized by uncontrolled growth of MC and resistance to conventional drugs. ...Growth-inhibitory effects of TK inhibitors were also observed in primary neoplastic mast cells, although IC …
Aggressive mast cell (MC) tumors are hematopoietic neoplasms characterized by uncontrolled growth of MC and resistance to conv …
Cellular proliferation in canine cutaneous mast cell tumors: associations with c-KIT and its role in prognostication.
Webster JD, Yuzbasiyan-Gurkan V, Miller RA, Kaneene JB, Kiupel M. Webster JD, et al. Among authors: yuzbasiyan gurkan v. Vet Pathol. 2007 May;44(3):298-308. doi: 10.1354/vp.44-3-298. Vet Pathol. 2007. PMID: 17491070
Canine cutaneous mast cell tumor (MCT) is a common neoplastic disease in dogs. Due to the prevalence of canine MCTs and the variable biologic behavior of this disease, accurate prognostication and a thorough understanding of MCT biology are critical for the treatmen …
Canine cutaneous mast cell tumor (MCT) is a common neoplastic disease in dogs. Due to the prevalence of canine MCTs and the va …
The role of c-KIT in tumorigenesis: evaluation in canine cutaneous mast cell tumors.
Webster JD, Yuzbasiyan-Gurkan V, Kaneene JB, Miller R, Resau JH, Kiupel M. Webster JD, et al. Among authors: yuzbasiyan gurkan v. Neoplasia. 2006 Feb;8(2):104-11. doi: 10.1593/neo.05622. Neoplasia. 2006. PMID: 16611403 Free PMC article.
The c-KIT proto-oncogene has been implicated in the pathogenesis of several neoplastic diseases, including gastrointestinal stromal tumors and mastocytosis in humans, and mast cell tumors (MCTs) in canines. Cutaneous MCTs are common neoplasms in dogs and have a vari …
The c-KIT proto-oncogene has been implicated in the pathogenesis of several neoplastic diseases, including gastrointestinal stromal tumors a …
14 results