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14 results

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Page 1
CRISPR screens decode cancer cell pathways that trigger γδ T cell detection.
Mamedov MR, Vedova S, Freimer JW, Sahu AD, Ramesh A, Arce MM, Meringa AD, Ota M, Chen PA, Hanspers K, Nguyen VQ, Takeshima KA, Rios AC, Pritchard JK, Kuball J, Sebestyen Z, Adams EJ, Marson A. Mamedov MR, et al. Among authors: sebestyen z. Nature. 2023 Sep;621(7977):188-195. doi: 10.1038/s41586-023-06482-x. Epub 2023 Aug 30. Nature. 2023. PMID: 37648854 Free PMC article.
Uncovering the mode of action of engineered T cells in patient cancer organoids.
Dekkers JF, Alieva M, Cleven A, Keramati F, Wezenaar AKL, van Vliet EJ, Puschhof J, Brazda P, Johanna I, Meringa AD, Rebel HG, Buchholz MB, Barrera Román M, Zeeman AL, de Blank S, Fasci D, Geurts MH, Cornel AM, Driehuis E, Millen R, Straetemans T, Nicolasen MJT, Aarts-Riemens T, Ariese HCR, Johnson HR, van Ineveld RL, Karaiskaki F, Kopper O, Bar-Ephraim YE, Kretzschmar K, Eggermont AMM, Nierkens S, Wehrens EJ, Stunnenberg HG, Clevers H, Kuball J, Sebestyen Z, Rios AC. Dekkers JF, et al. Among authors: sebestyen z. Nat Biotechnol. 2023 Jan;41(1):60-69. doi: 10.1038/s41587-022-01397-w. Epub 2022 Jul 25. Nat Biotechnol. 2023. PMID: 35879361 Free PMC article.
Identification of a tumor-specific allo-HLA-restricted γδTCR.
Kierkels GJJ, Scheper W, Meringa AD, Johanna I, Beringer DX, Janssen A, Schiffler M, Aarts-Riemens T, Kramer L, Straetemans T, Heijhuurs S, Leusen JHW, San José E, Fuchs K, Griffioen M, Falkenburg JH, Bongiovanni L, de Bruin A, Vargas-Diaz D, Altelaar M, Heck AJR, Shultz LD, Ishikawa F, Nishimura MI, Sebestyén Z, Kuball J. Kierkels GJJ, et al. Among authors: sebestyen z. Blood Adv. 2019 Oct 8;3(19):2870-2882. doi: 10.1182/bloodadvances.2019032409. Blood Adv. 2019. PMID: 31585951 Free PMC article.
Synthesis of gamma-L-glutamyl-taurine.
Sebestyén F, Furka A, Feuer L, Gulyás J, Szókán G. Sebestyén F, et al. Int J Pept Protein Res. 1980 Oct;16(4):245-7. Int J Pept Protein Res. 1980. PMID: 7193190
Glu(Tau), a bioactive substance previously isolated from the protein free aqueous extract of bovine parathyroid powder, has been synthesized. The intermediate derivative Z-Glu(Tau)-OBzl was prepared in three different ways from Z-Glu-OBzl and (1) cystamine by using …
Glu(Tau), a bioactive substance previously isolated from the protein free aqueous extract of bovine parathyroid powder, has been synthesized …
Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Kierkels GJJ, van Diest E, Hernández-López P, Scheper W, de Bruin ACM, Frijlink E, Aarts-Riemens T, van Dooremalen SFJ, Beringer DX, Oostvogels R, Kramer L, Straetemans T, Uckert W, Sebestyén Z, Kuball J. Kierkels GJJ, et al. Among authors: sebestyen z. Mol Ther Methods Clin Dev. 2021 Jun 24;22:388-400. doi: 10.1016/j.omtm.2021.06.011. eCollection 2021 Sep 10. Mol Ther Methods Clin Dev. 2021. PMID: 34514030 Free PMC article.
Mapping T cell dynamics to molecular profiles through behavior-guided transcriptomics.
Wezenaar AKL, Pandey U, Keramati F, Hernandez-Roca M, Brazda P, Barrera Román M, Cleven A, Karaiskaki F, Aarts-Riemens T, de Blank S, Hernandez-Lopez P, Heijhuurs S, Alemany A, Kuball J, Sebestyen Z, Dekkers JF, Stunnenberg HG, Alieva M, Rios AC. Wezenaar AKL, et al. Among authors: sebestyen z. Nat Protoc. 2025 Feb 10. doi: 10.1038/s41596-024-01126-4. Online ahead of print. Nat Protoc. 2025. PMID: 39930061 Review.
Different ways to induce apoptosis by fenretinide and all-trans-retinoic acid in human B lymphoma cells.
Barna G, Sebestyén A, Weischede S, Peták I, Mihalik R, Formelli F, Kopper L. Barna G, et al. Among authors: sebestyen a. Anticancer Res. 2005 Nov-Dec;25(6B):4179-85. Anticancer Res. 2005. PMID: 16309214 Free article.
The depolarization of the mitochondrial membrane occured earlier after ATRA than after 4HPR treament. Z-VAD-fmk, the general caspase inhibitor, decreased the DNA fragmentation in ATRA-treated cells, but simultaneously increased necrosis. However, z-VAD-fmk did not i …
The depolarization of the mitochondrial membrane occured earlier after ATRA than after 4HPR treament. Z-VAD-fmk, the general caspase …
Conkiss: conformal kidneys sparing 3D noncoplanar radiotherapy treatment for pancreatic cancer as an alternative to IMRT.
Sebestyén Z, Kovács P, Gulybán Á, Farkas R, Bellyei S, Liposits G, Szigeti A, Esik O, Dérczy K, Mangel L. Sebestyén Z, et al. Med Dosim. 2011 Spring;36(1):35-40. doi: 10.1016/j.meddos.2009.11.001. Epub 2010 Jan 22. Med Dosim. 2011. PMID: 20097060 Clinical Trial.
The aimed organs at risk (OARs) mean dose limits were: kidney <12 Gy, liver <25 Gy, small bowels <30 Gy, and spinal cord maximum <45 Gy. Conformity and homogeneity indexes with z-test were used to evaluate and compare the different planning approaches. The mean …
The aimed organs at risk (OARs) mean dose limits were: kidney <12 Gy, liver <25 Gy, small bowels <30 Gy, and spinal cord maximum &l …
14 results