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Year Number of Results
2009 2
2010 1
2011 1
2015 1
2018 2
2021 0
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Page 1
Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors.
Marzi L, Agama K, Murai J, Difilippantonio S, James A, Peer CJ, Figg WD, Beck D, Elsayed MSA, Cushman M, Pommier Y. Marzi L, et al. Mol Cancer Ther. 2018 Aug;17(8):1694-1704. doi: 10.1158/1535-7163.MCT-18-0028. Epub 2018 May 10. Mol Cancer Ther. 2018. PMID: 29748210 Free PMC article.
DNA topoisomerase I inhibitors: chemistry, biology, and interfacial inhibition.
Pommier Y. Pommier Y. Chem Rev. 2009 Jul;109(7):2894-902. doi: 10.1021/cr900097c. Chem Rev. 2009. PMID: 19476377 Free PMC article. Review. No abstract available.
Synthesis and structure-activity relationship of furoquinolinediones as inhibitors of Tyrosyl-DNA phosphodiesterase 2 (TDP2).
Yu LM, Hu Z, Chen Y, Ravji A, Lopez S, Plescia CB, Yu Q, Yang H, Abdelmalak M, Saha S, Agama K, Kiselev E, Marchand C, Pommier Y, An LK. Yu LM, et al. Eur J Med Chem. 2018 May 10;151:777-796. doi: 10.1016/j.ejmech.2018.04.024. Epub 2018 Apr 12. Eur J Med Chem. 2018. PMID: 29677635 Free PMC article.
Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors.
Seol Y, Zhang H, Agama K, Lorence N, Pommier Y, Neuman KC. Seol Y, et al. Mol Cancer Ther. 2015 Nov;14(11):2552-9. doi: 10.1158/1535-7163.MCT-15-0454. Epub 2015 Sep 8. Mol Cancer Ther. 2015. PMID: 26351326 Free PMC article.
Molecular and cellular pharmacology of the novel noncamptothecin topoisomerase I inhibitor Genz-644282.
Sooryakumar D, Dexheimer TS, Teicher BA, Pommier Y. Sooryakumar D, et al. Mol Cancer Ther. 2011 Aug;10(8):1490-9. doi: 10.1158/1535-7163.MCT-10-1043. Epub 2011 Jun 2. Mol Cancer Ther. 2011. PMID: 21636699 Free PMC article.
The indenoisoquinoline noncamptothecin topoisomerase I inhibitors: update and perspectives.
Pommier Y, Cushman M. Pommier Y, et al. Mol Cancer Ther. 2009 May;8(5):1008-14. doi: 10.1158/1535-7163.MCT-08-0706. Epub 2009 Apr 21. Mol Cancer Ther. 2009. PMID: 19383846 Free PMC article.
A novel DNA topoisomerase I inhibitor with different mechanism from camptothecin induces G2/M phase cell cycle arrest to K562 cells.
Wu N, Wu XW, Agama K, Pommier Y, Du J, Li D, Gu LQ, Huang ZS, An LK. Wu N, et al. Biochemistry. 2010 Nov 30;49(47):10131-6. doi: 10.1021/bi1009419. Epub 2010 Nov 8. Biochemistry. 2010. PMID: 21033700 Free PMC article.
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