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Crowdsourced analysis of clinical trial data to predict amyotrophic lateral sclerosis progression.
Küffner R, Zach N, Norel R, Hawe J, Schoenfeld D, Wang L, Li G, Fang L, Mackey L, Hardiman O, Cudkowicz M, Sherman A, Ertaylan G, Grosse-Wentrup M, Hothorn T, van Ligtenberg J, Macke JH, Meyer T, Schölkopf B, Tran L, Vaughan R, Stolovitzky G, Leitner ML. Küffner R, et al. Among authors: zach n. Nat Biotechnol. 2015 Jan;33(1):51-7. doi: 10.1038/nbt.3051. Epub 2014 Nov 2. Nat Biotechnol. 2015. PMID: 25362243
Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach.
Kueffner R, Zach N, Bronfeld M, Norel R, Atassi N, Balagurusamy V, Di Camillo B, Chio A, Cudkowicz M, Dillenberger D, Garcia-Garcia J, Hardiman O, Hoff B, Knight J, Leitner ML, Li G, Mangravite L, Norman T, Wang L; ALS Stratification Consortium; Xiao J, Fang WC, Peng J, Yang C, Chang HJ, Stolovitzky G. Kueffner R, et al. Among authors: zach n. Sci Rep. 2019 Jan 24;9(1):690. doi: 10.1038/s41598-018-36873-4. Sci Rep. 2019. PMID: 30679616 Free PMC article.
Item response theory analysis of the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised in the Pooled Resource Open-Access ALS Clinical Trials Database.
Bacci ED, Staniewska D, Coyne KS, Boyer S, White LA, Zach N, Cedarbaum JM; Pooled Resource Open-Access ALS Clinical Trials Consortium. Bacci ED, et al. Among authors: zach n. Amyotroph Lateral Scler Frontotemporal Degener. 2016;17(3-4):157-67. doi: 10.3109/21678421.2015.1095930. Epub 2015 Oct 16. Amyotroph Lateral Scler Frontotemporal Degener. 2016. PMID: 26473473
Being PRO-ACTive: What can a Clinical Trial Database Reveal About ALS?
Zach N, Ennist DL, Taylor AA, Alon H, Sherman A, Kueffner R, Walker J, Sinani E, Katsovskiy I, Cudkowicz M, Leitner ML. Zach N, et al. Neurotherapeutics. 2015 Apr;12(2):417-23. doi: 10.1007/s13311-015-0336-z. Neurotherapeutics. 2015. PMID: 25613183 Free PMC article. Review.
The PRO-ACT database: design, initial analyses, and predictive features.
Atassi N, Berry J, Shui A, Zach N, Sherman A, Sinani E, Walker J, Katsovskiy I, Schoenfeld D, Cudkowicz M, Leitner M. Atassi N, et al. Among authors: zach n. Neurology. 2014 Nov 4;83(19):1719-25. doi: 10.1212/WNL.0000000000000951. Epub 2014 Oct 8. Neurology. 2014. PMID: 25298304 Free PMC article.
Design and analysis of a clinical trial using previous trials as historical control.
Schoenfeld DA, Finkelstein DM, Macklin E, Zach N, Ennist DL, Taylor AA, Atassi N; Pooled Resource Open-Access ALS Clinical Trials Consortium. Schoenfeld DA, et al. Among authors: zach n. Clin Trials. 2019 Oct;16(5):531-538. doi: 10.1177/1740774519858914. Epub 2019 Jul 1. Clin Trials. 2019. PMID: 31256630 Free PMC article.
PRO-ACTive sharing of clinical data.
Zach N, Leitner ML. Zach N, et al. Nat Biotechnol. 2022 Jul;40(7):999-1000. doi: 10.1038/s41587-022-01395-y. Nat Biotechnol. 2022. PMID: 35778617 No abstract available.
32 results