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γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A.
Gao X, Zhao L, Liu S, Li Y, Xia S, Chen D, Wang M, Wu S, Dai Q, Vu H, Zacharias L, DeBerardinis R, Lim E, Metallo C, Boggon TJ, Lonial S, Lin R, Mao H, Pan Y, Shan C, Chen J. Gao X, et al. Among authors: zacharias l. Mol Cell. 2019 Dec 19;76(6):857-871.e9. doi: 10.1016/j.molcel.2019.09.007. Epub 2019 Oct 2. Mol Cell. 2019. PMID: 31586547 Free PMC article.
Lactate Metabolism in Human Lung Tumors.
Faubert B, Li KY, Cai L, Hensley CT, Kim J, Zacharias LG, Yang C, Do QN, Doucette S, Burguete D, Li H, Huet G, Yuan Q, Wigal T, Butt Y, Ni M, Torrealba J, Oliver D, Lenkinski RE, Malloy CR, Wachsmann JW, Young JD, Kernstine K, DeBerardinis RJ. Faubert B, et al. Among authors: zacharias lg. Cell. 2017 Oct 5;171(2):358-371.e9. doi: 10.1016/j.cell.2017.09.019. Cell. 2017. PMID: 28985563 Free PMC article.
Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers.
Huang F, Ni M, Chalishazar MD, Huffman KE, Kim J, Cai L, Shi X, Cai F, Zacharias LG, Ireland AS, Li K, Gu W, Kaushik AK, Liu X, Gazdar AF, Oliver TG, Minna JD, Hu Z, DeBerardinis RJ. Huang F, et al. Among authors: zacharias lg. Cell Metab. 2018 Sep 4;28(3):369-382.e5. doi: 10.1016/j.cmet.2018.06.005. Epub 2018 Jun 28. Cell Metab. 2018. PMID: 30043754 Free PMC article.
Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity.
DeVorkin L, Pavey N, Carleton G, Comber A, Ho C, Lim J, McNamara E, Huang H, Kim P, Zacharias LG, Mizushima N, Saitoh T, Akira S, Beckham W, Lorzadeh A, Moksa M, Cao Q, Murthy A, Hirst M, DeBerardinis RJ, Lum JJ. DeVorkin L, et al. Among authors: zacharias lg. Cell Rep. 2019 Apr 9;27(2):502-513.e5. doi: 10.1016/j.celrep.2019.03.037. Cell Rep. 2019. PMID: 30970253 Free article.
Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans.
Ni M, Solmonson A, Pan C, Yang C, Li D, Notzon A, Cai L, Guevara G, Zacharias LG, Faubert B, Vu HS, Jiang L, Ko B, Morales NM, Pei J, Vale G, Rakheja D, Grishin NV, McDonald JG, Gotway GK, McNutt MC, Pascual JM, DeBerardinis RJ. Ni M, et al. Among authors: zacharias lg. Cell Rep. 2019 Apr 30;27(5):1376-1386.e6. doi: 10.1016/j.celrep.2019.04.005. Cell Rep. 2019. PMID: 31042466 Free PMC article.
Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation.
Hao YH, Lafita-Navarro MC, Zacharias L, Borenstein-Auerbach N, Kim M, Barnes S, Kim J, Shay J, DeBerardinis RJ, Conacci-Sorrell M. Hao YH, et al. Among authors: zacharias l. Cell Commun Signal. 2019 Oct 17;17(1):129. doi: 10.1186/s12964-019-0444-1. Cell Commun Signal. 2019. PMID: 31623618 Free PMC article.
143 results