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TGF-beta-induced expression of tissue inhibitor of metalloproteinases-3 gene in chondrocytes is mediated by extracellular signal-regulated kinase pathway and Sp1 transcription factor.
Qureshi HY, Sylvester J, El Mabrouk M, Zafarullah M. Qureshi HY, et al. Among authors: zafarullah m. J Cell Physiol. 2005 May;203(2):345-52. doi: 10.1002/jcp.20228. J Cell Physiol. 2005. PMID: 15468069
Role of Sp1 transcription factor in Interleukin-1-induced ADAMTS-4 (aggrecanase-1) gene expression in human articular chondrocytes.
Sylvester J, Ahmad R, Zafarullah M. Sylvester J, et al. Among authors: zafarullah m. Rheumatol Int. 2013 Feb;33(2):517-22. doi: 10.1007/s00296-011-2187-1. Epub 2011 Nov 8. Rheumatol Int. 2013. PMID: 22065068
Tissue inhibitor of metalloproteinases-4 (TIMP-4) gene expression is increased in human osteoarthritic femoral head cartilage.
Huang W, Li WQ, Dehnade F, Zafarullah M. Huang W, et al. Among authors: zafarullah m. J Cell Biochem. 2002;85(2):295-303. doi: 10.1002/jcb.10138. J Cell Biochem. 2002. PMID: 11948685
Interleukin-1 induction of aggrecanase gene expression in human articular chondrocytes is mediated by mitogen-activated protein kinases.
Sylvester J, El Mabrouk M, Ahmad R, Chaudry A, Zafarullah M. Sylvester J, et al. Among authors: zafarullah m. Cell Physiol Biochem. 2012;30(3):563-74. doi: 10.1159/000341438. Epub 2012 Jul 23. Cell Physiol Biochem. 2012. PMID: 22832115 Free article.
Enhanced expression of tissue inhibitor of metalloproteinases-4 gene in human osteoarthritic synovial membranes and its differential regulation by cytokines in chondrocytes.
Huang W, Mabrouk ME, Sylvester J, Dehnade F, Zafarullah M. Huang W, et al. Among authors: zafarullah m. Open Rheumatol J. 2011;5:81-7. doi: 10.2174/1874312901105010081. Epub 2011 Nov 29. Open Rheumatol J. 2011. PMID: 22216069 Free PMC article.
Involvement of H-Ras and reactive oxygen species in proinflammatory cytokine-induced matrix metalloproteinase-13 expression in human articular chondrocytes.
Ahmad R, Sylvester J, Ahmad M, Zafarullah M. Ahmad R, et al. Among authors: zafarullah m. Arch Biochem Biophys. 2011 Mar 15;507(2):350-5. doi: 10.1016/j.abb.2010.12.032. Epub 2011 Jan 3. Arch Biochem Biophys. 2011. PMID: 21211511
Adaptor proteins and Ras synergistically regulate IL-1-induced ADAMTS-4 expression in human chondrocytes.
Ahmad R, Sylvester J, Ahmad M, Zafarullah M. Ahmad R, et al. Among authors: zafarullah m. J Immunol. 2009 Apr 15;182(8):5081-7. doi: 10.4049/jimmunol.0803544. J Immunol. 2009. PMID: 19342688
High-efficiency transfection of nucleic acids by the modified calcium phosphate precipitation method in chondrocytes.
Qureshi HY, Ahmad R, Zafarullah M. Qureshi HY, et al. Among authors: zafarullah m. Anal Biochem. 2008 Nov 15;382(2):138-40. doi: 10.1016/j.ab.2008.07.027. Epub 2008 Jul 31. Anal Biochem. 2008. PMID: 18703012
Smad signaling pathway is a pivotal component of tissue inhibitor of metalloproteinases-3 regulation by transforming growth factor beta in human chondrocytes.
Qureshi HY, Ricci G, Zafarullah M. Qureshi HY, et al. Among authors: zafarullah m. Biochim Biophys Acta. 2008 Sep;1783(9):1605-12. doi: 10.1016/j.bbamcr.2008.04.005. Epub 2008 Apr 18. Biochim Biophys Acta. 2008. PMID: 18471442
MyD88, IRAK1 and TRAF6 knockdown in human chondrocytes inhibits interleukin-1-induced matrix metalloproteinase-13 gene expression and promoter activity by impairing MAP kinase activation.
Ahmad R, Sylvester J, Zafarullah M. Ahmad R, et al. Among authors: zafarullah m. Cell Signal. 2007 Dec;19(12):2549-57. doi: 10.1016/j.cellsig.2007.08.013. Epub 2007 Aug 25. Cell Signal. 2007. PMID: 17905570
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