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Both early and delayed treatment with melanocortin 4 receptor-stimulating melanocortins produces neuroprotection in cerebral ischemia.
Giuliani D, Mioni C, Altavilla D, Leone S, Bazzani C, Minutoli L, Bitto A, Cainazzo MM, Marini H, Zaffe D, Botticelli AR, Pizzala R, Savio M, Necchi D, Schiöth HB, Bertolini A, Squadrito F, Guarini S. Giuliani D, et al. Among authors: zaffe d. Endocrinology. 2006 Mar;147(3):1126-35. doi: 10.1210/en.2005-0692. Epub 2005 Oct 27. Endocrinology. 2006. PMID: 16254026
Activation of an efferent cholinergic pathway produces strong protection against myocardial ischemia/reperfusion injury in rats.
Mioni C, Bazzani C, Giuliani D, Altavilla D, Leone S, Ferrari A, Minutoli L, Bitto A, Marini H, Zaffe D, Botticelli AR, Iannone A, Tomasi A, Bigiani A, Bertolini A, Squadrito F, Guarini S. Mioni C, et al. Among authors: zaffe d. Crit Care Med. 2005 Nov;33(11):2621-8. doi: 10.1097/01.ccm.0000186762.05301.13. Crit Care Med. 2005. Retraction in: Crit Care Med. 2023 Mar 1;51(3):e90. doi: 10.1097/CCM.0000000000005779 PMID: 16276189 Retracted.
Broad therapeutic treatment window of [Nle(4), D-Phe(7)]alpha-melanocyte-stimulating hormone for long-lasting protection against ischemic stroke, in Mongolian gerbils.
Giuliani D, Leone S, Mioni C, Bazzani C, Zaffe D, Botticelli AR, Altavilla D, Galantucci M, Minutoli L, Bitto A, Squadrito F, Guarini S. Giuliani D, et al. Among authors: zaffe d. Eur J Pharmacol. 2006 May 24;538(1-3):48-56. doi: 10.1016/j.ejphar.2006.03.038. Epub 2006 Mar 24. Eur J Pharmacol. 2006. PMID: 16647700
Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage.
Giuliani D, Mioni C, Bazzani C, Zaffe D, Botticelli AR, Capolongo S, Sabba A, Galantucci M, Iannone A, Grieco P, Novellino E, Colombo G, Tomasi A, Catania A, Guarini S. Giuliani D, et al. Among authors: zaffe d. Br J Pharmacol. 2007 Mar;150(5):595-603. doi: 10.1038/sj.bjp.0707115. Epub 2007 Jan 22. Br J Pharmacol. 2007. PMID: 17245369 Free PMC article.
125 results