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A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart.
Iyer LM, Nagarajan S, Woelfer M, Schoger E, Khadjeh S, Zafiriou MP, Kari V, Herting J, Pang ST, Weber T, Rathjens FS, Fischer TH, Toischer K, Hasenfuss G, Noack C, Johnsen SA, Zelarayán LC. Iyer LM, et al. Among authors: Zafiriou MP. Nucleic Acids Res. 2018 Apr 6;46(6):2850-2867. doi: 10.1093/nar/gky049. Nucleic Acids Res. 2018. PMID: 29394407 Free PMC article.
Krueppel-like factor 15 regulates Wnt/β-catenin transcription and controls cardiac progenitor cell fate in the postnatal heart.
Noack C, Zafiriou MP, Schaeffer HJ, Renger A, Pavlova E, Dietz R, Zimmermann WH, Bergmann MW, Zelarayán LC. Noack C, et al. Among authors: Zafiriou MP. EMBO Mol Med. 2012 Sep;4(9):992-1007. doi: 10.1002/emmm.201101043. Epub 2012 Jul 5. EMBO Mol Med. 2012. PMID: 22767436 Free PMC article.
The four and a half LIM-domain 2 controls early cardiac cell commitment and expansion via regulating β-catenin-dependent transcription.
Renger A, Zafiriou MP, Noack C, Pavlova E, Becker A, Sharkova K, Bergmann MW, El-Armouche A, Zimmermann WH, Zelarayán LC. Renger A, et al. Among authors: Zafiriou MP. Stem Cells. 2013 May;31(5):928-40. doi: 10.1002/stem.1332. Stem Cells. 2013. PMID: 23341242 Free PMC article.
NF-kappaB activation is required for adaptive cardiac hypertrophy.
Zelarayan L, Renger A, Noack C, Zafiriou MP, Gehrke C, van der Nagel R, Dietz R, de Windt L, Bergmann MW. Zelarayan L, et al. Among authors: Zafiriou MP. Cardiovasc Res. 2009 Dec 1;84(3):416-24. doi: 10.1093/cvr/cvp237. Epub 2009 Jul 20. Cardiovasc Res. 2009. PMID: 19620128
Beta-Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation.
Zelarayán LC, Noack C, Sekkali B, Kmecova J, Gehrke C, Renger A, Zafiriou MP, van der Nagel R, Dietz R, de Windt LJ, Balligand JL, Bergmann MW. Zelarayán LC, et al. Among authors: Zafiriou MP. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19762-7. doi: 10.1073/pnas.0808393105. Epub 2008 Dec 10. Proc Natl Acad Sci U S A. 2008. PMID: 19073933 Free PMC article.
Hepoxilin A3 synthase.
Nigam S, Zafiriou MP. Nigam S, et al. Among authors: Zafiriou MP. Biochem Biophys Res Commun. 2005 Dec 9;338(1):161-8. doi: 10.1016/j.bbrc.2005.09.065. Epub 2005 Sep 21. Biochem Biophys Res Commun. 2005. PMID: 16198304 Review.
Hepoxilin A3 (HXA3) synthase deficiency is causative of a novel ichthyosis form.
Nigam S, Zafiriou MP, Deva R, Kerstin N, Geilen C, Ciccoli R, Sczepanski M, Lohse M. Nigam S, et al. Among authors: Zafiriou MP. FEBS Lett. 2008 Jan 23;582(2):279-85. doi: 10.1016/j.febslet.2007.12.017. Epub 2007 Dec 18. FEBS Lett. 2008. PMID: 18086569
Structure, biochemistry and biology of hepoxilins: an update.
Nigam S, Zafiriou MP, Deva R, Ciccoli R, Roux-Van der Merwe R. Nigam S, et al. Among authors: Zafiriou MP. FEBS J. 2007 Jul;274(14):3503-3512. doi: 10.1111/j.1742-4658.2007.05910.x. Epub 2007 Jul 2. FEBS J. 2007. PMID: 17608719 Review.
Oxygenation by COX-2 (cyclo-oxygenase-2) of 3-HETE (3-hydroxyeicosatetraenoic acid), a fungal mimetic of arachidonic acid, produces a cascade of novel bioactive 3-hydroxyeicosanoids.
Ciccoli R, Sahi S, Singh S, Prakash H, Zafiriou MP, Ishdorj G, Kock JL, Nigam S. Ciccoli R, et al. Among authors: Zafiriou MP. Biochem J. 2005 Sep 15;390(Pt 3):737-47. doi: 10.1042/BJ20041995. Biochem J. 2005. PMID: 15869467 Free PMC article.
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