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Opioid growth factor and the treatment of human pancreatic cancer: a review.
Zagon IS, McLaughlin PJ. Zagon IS, et al. World J Gastroenterol. 2014 Mar 7;20(9):2218-23. doi: 10.3748/wjg.v20.i9.2218. World J Gastroenterol. 2014. PMID: 24605021 Free PMC article. Review.
Molecular manipulation of OGFr confirms that the receptor is specific for OGF's inhibitory action. Preclinical studies have warranted Phase I and Phase II clinical trials using OGF infusions as a treatment for patients with advanced, unresectable pancreatic cancers. OGF, a …
Molecular manipulation of OGFr confirms that the receptor is specific for OGF's inhibitory action. Preclinical studies have warranted …
An opioid growth factor regulates the replication of microorganisms.
Zagon IS, McLaughlin PJ. Zagon IS, et al. Life Sci. 1992;50(16):1179-87. doi: 10.1016/0024-3205(92)90461-w. Life Sci. 1992. PMID: 1313136
This effect on growth involves cell proliferative events and is under tonic control, since potent opioid antagonists accelerate cell replication. ...
This effect on growth involves cell proliferative events and is under tonic control, since potent opioid antagonists accelerate cell …
Ontogeny of zeta (zeta), the opioid growth factor receptor, in the rat brain.
Zagon IS, Gibo DM, McLaughlin PJ. Zagon IS, et al. Brain Res. 1992 Nov 20;596(1-2):149-56. doi: 10.1016/0006-8993(92)91542-m. Brain Res. 1992. PMID: 1334774
Opioid growth factor (OGF), [Met5]enkephalin, serves as an inhibitory influence on the developing nervous system and is especially targeted to cell proliferative events. ...
Opioid growth factor (OGF), [Met5]enkephalin, serves as an inhibitory influence on the developing nervous system and is especially ta …
Endogenous opioids regulate cell proliferation in the retina of developing rat.
Isayama T, McLaughlin PJ, Zagon IS. Isayama T, et al. Brain Res. 1991 Mar 22;544(1):79-85. doi: 10.1016/0006-8993(91)90887-2. Brain Res. 1991. PMID: 1649664
Adult and developing human cerebella exhibit different profiles of opioid binding sites.
Zagon IS, Gibo DM, McLaughlin PJ. Zagon IS, et al. Brain Res. 1990 Jul 16;523(1):62-8. doi: 10.1016/0006-8993(90)91635-t. Brain Res. 1990. PMID: 2169964
Although the function of mu-, delta-, and kappa-receptors in human cerebellum are unclear, the growth-related zeta-receptor is present at a time of cell replication and differentiation but is not detected in mature cerebellum....
Although the function of mu-, delta-, and kappa-receptors in human cerebellum are unclear, the growth-related zeta-receptor is presen …
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