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Page 1
Grignard-mediated synthesis and preliminary biological evaluation of novel 3-substituted farnesyl diphosphate analogues.
Zahn TJ, Weinbaum C, Gibbs RA. Zahn TJ, et al. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1763-6. doi: 10.1016/s0960-894x(00)00337-1. Bioorg Med Chem Lett. 2000. PMID: 10937743
Interplay of isoprenoid and peptide substrate specificity in protein farnesyltransferase.
Reigard SA, Zahn TJ, Haworth KB, Hicks KA, Fierke CA, Gibbs RA. Reigard SA, et al. Among authors: zahn tj. Biochemistry. 2005 Aug 23;44(33):11214-23. doi: 10.1021/bi050725l. Biochemistry. 2005. PMID: 16101305
Non-peptidic prenyltransferase inhibitors: diverse structural classes and surprising anti-cancer mechanisms.
Gibbs RA, Zahn TJ, Sebolt-Leopold JS. Gibbs RA, et al. Among authors: zahn tj. Curr Med Chem. 2001 Oct;8(12):1437-65. doi: 10.2174/0929867013372111. Curr Med Chem. 2001. PMID: 11562276 Review.
Synthesis and evaluation of GGPP geometric isomers: divergent substrate specificities of FTase and GGTase I.
Zahn TJ, Whitney J, Weinbaum C, Gibbs RA. Zahn TJ, et al. Bioorg Med Chem Lett. 2001 Jun 18;11(12):1605-8. doi: 10.1016/s0960-894x(01)00292-x. Bioorg Med Chem Lett. 2001. PMID: 11412990
Novel limonene phosphonate and farnesyl diphosphate analogues: design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors.
Eummer JT, Gibbs BS, Zahn TJ, Sebolt-Leopold JS, Gibbs RA. Eummer JT, et al. Among authors: zahn tj. Bioorg Med Chem. 1999 Feb;7(2):241-50. doi: 10.1016/s0968-0896(98)00202-8. Bioorg Med Chem. 1999. PMID: 10218815
Novel farnesol and geranylgeraniol analogues: A potential new class of anticancer agents directed against protein prenylation.
Gibbs BS, Zahn TJ, Mu Y, Sebolt-Leopold JS, Gibbs RA. Gibbs BS, et al. Among authors: zahn tj. J Med Chem. 1999 Sep 23;42(19):3800-8. doi: 10.1021/jm9902786. J Med Chem. 1999. PMID: 10508429
Computational and conformational evaluation of FTase alternative substrates: insight into a novel enzyme binding pocket.
Henriksen BS, Zahn TJ, Evanseck JD, Firestine SM, Gibbs RA. Henriksen BS, et al. Among authors: zahn tj. J Chem Inf Model. 2005 Jul-Aug;45(4):1047-52. doi: 10.1021/ci0496550. J Chem Inf Model. 2005. PMID: 16045300
The effect of protein intake on maximum urine and renal tissue water-solute concentrations in the muskrat (Ondatra zibethica osoyoosensis, Lord).
Zahn TJ. Zahn TJ. Comp Biochem Physiol. 1968 Jun;25(3):1021-33. doi: 10.1016/0010-406x(68)90588-4. Comp Biochem Physiol. 1968. PMID: 5758863 No abstract available.