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CTLA-4 directly inhibits osteoclast formation.
Axmann R, Herman S, Zaiss M, Franz S, Polzer K, Zwerina J, Herrmann M, Smolen J, Schett G. Axmann R, et al. Ann Rheum Dis. 2008 Nov;67(11):1603-9. doi: 10.1136/ard.2007.080713. Epub 2008 Jan 18. Ann Rheum Dis. 2008. PMID: 18203760
12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis.
Krönke G, Katzenbeisser J, Uderhardt S, Zaiss MM, Scholtysek C, Schabbauer G, Zarbock A, Koenders MI, Axmann R, Zwerina J, Baenckler HW, van den Berg W, Voll RE, Kühn H, Joosten LA, Schett G. Krönke G, et al. Among authors: zaiss mm. J Immunol. 2009 Sep 1;183(5):3383-9. doi: 10.4049/jimmunol.0900327. Epub 2009 Aug 12. J Immunol. 2009. PMID: 19675173 Free article.
The alpha-isoform of p38 MAPK specifically regulates arthritic bone loss.
Böhm C, Hayer S, Kilian A, Zaiss MM, Finger S, Hess A, Engelke K, Kollias G, Krönke G, Zwerina J, Schett G, David JP. Böhm C, et al. Among authors: zaiss mm. J Immunol. 2009 Nov 1;183(9):5938-47. doi: 10.4049/jimmunol.0901026. Epub 2009 Oct 14. J Immunol. 2009. PMID: 19828631
R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway.
Krönke G, Uderhardt S, Kim KA, Stock M, Scholtysek C, Zaiss MM, Surmann-Schmitt C, Luther J, Katzenbeisser J, David JP, Abdollahi-Roodsaz S, Tran K, Bright JM, Binnerts ME, Akhmetshina A, Böhm C, Distler JH, Joosten LA, Schett G, Abo A. Krönke G, et al. Among authors: zaiss mm. Arthritis Rheum. 2010 Aug;62(8):2303-12. doi: 10.1002/art.27496. Arthritis Rheum. 2010. PMID: 20506554 Free article.
Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells.
Schulze J, Bickert T, Beil FT, Zaiss MM, Albers J, Wintges K, Streichert T, Klaetschke K, Keller J, Hissnauer TN, Spiro AS, Gessner A, Schett G, Amling M, McKenzie AN, Horst AK, Schinke T. Schulze J, et al. Among authors: zaiss mm. J Bone Miner Res. 2011 Apr;26(4):704-17. doi: 10.1002/jbmr.269. J Bone Miner Res. 2011. PMID: 20939024 Free article.
71 results