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Molecular pharmacology of high voltage-activated calcium channels.
Doering CJ, Zamponi GW. Doering CJ, et al. Among authors: zamponi gw. J Bioenerg Biomembr. 2003 Dec;35(6):491-505. doi: 10.1023/b:jobb.0000008022.50702.1a. J Bioenerg Biomembr. 2003. PMID: 15000518 Review.
Amine blockers of the cytoplasmic mouth of sodium channels: a small structural change can abolish voltage dependence.
Zamponi GW, French RJ. Zamponi GW, et al. Biophys J. 1994 Sep;67(3):1015-27. doi: 10.1016/S0006-3495(94)80567-3. Biophys J. 1994. PMID: 7811912 Free PMC article.
Transcainide causes two modes of open-channel block with different voltage sensitivities in batrachotoxin-activated sodium channels.
Zamponi GW, French RJ. Zamponi GW, et al. Biophys J. 1994 Sep;67(3):1028-39. doi: 10.1016/S0006-3495(94)80568-5. Biophys J. 1994. PMID: 7811913 Free PMC article.
Phenomenologically, the bulky and complex transcainide molecule combines the almost voltage-insensitive blocking action of phenylhydrazine (Zamponi and French, 1994a (companion paper)) with a slow open-channel blocking action that shows a voltage dependence typical of simp …
Phenomenologically, the bulky and complex transcainide molecule combines the almost voltage-insensitive blocking action of phenylhydrazine ( …
Open-channel block by internally applied amines inhibits activation gate closure in batrachotoxin-activated sodium channels.
Zamponi GW, French RJ. Zamponi GW, et al. Biophys J. 1994 Sep;67(3):1040-51. doi: 10.1016/S0006-3495(94)80569-7. Biophys J. 1994. PMID: 7811914 Free PMC article.
Dual actions of procainamide on batrachotoxin-activated sodium channels: open channel block and prevention of inactivation.
Zamponi GW, Sui X, Codding PW, French RJ. Zamponi GW, et al. Biophys J. 1993 Dec;65(6):2324-34. doi: 10.1016/S0006-3495(93)81291-8. Biophys J. 1993. PMID: 8312472 Free PMC article.
Qualitatively, this block resembled the fast open-channel block by lidocaine (Zamponi, G. W., D. D. Doyle, and R. J. French. 1993. ...For the cardiac channels, procainamide reduced the frequency of transitions to a long-lived closed state which shows features characteristi …
Qualitatively, this block resembled the fast open-channel block by lidocaine (Zamponi, G. W., D. D. Doyle, and R. J. French. 1993. .. …
Dissecting lidocaine action: diethylamide and phenol mimic separate modes of lidocaine block of sodium channels from heart and skeletal muscle.
Zamponi GW, French RJ. Zamponi GW, et al. Biophys J. 1993 Dec;65(6):2335-47. doi: 10.1016/S0006-3495(93)81292-X. Biophys J. 1993. PMID: 8312473 Free PMC article.
Thus, although occurring at 15-fold higher concentrations, block by diethylamide closely resembles the fast mode of block by lidocaine (Zamponi, G. ...Thus, phenol block resembles the slow mode of block observed for lidocaine (Zamponi, G. W., D. D. Doyle, and R. J. …
Thus, although occurring at 15-fold higher concentrations, block by diethylamide closely resembles the fast mode of block by lidocaine (Z
Fast lidocaine block of cardiac and skeletal muscle sodium channels: one site with two routes of access.
Zamponi GW, Doyle DD, French RJ. Zamponi GW, et al. Biophys J. 1993 Jul;65(1):80-90. doi: 10.1016/S0006-3495(93)81042-7. Biophys J. 1993. PMID: 8396459 Free PMC article.
State-dependent block underlies the tissue specificity of lidocaine action on batrachotoxin-activated cardiac sodium channels.
Zamponi GW, Doyle DD, French RJ. Zamponi GW, et al. Biophys J. 1993 Jul;65(1):91-100. doi: 10.1016/S0006-3495(93)81043-9. Biophys J. 1993. PMID: 8396460 Free PMC article.
Sodium current inhibition by internal calcium: a combination of open-channel block and surface charge screening?
Zamponi GW, French RJ. Zamponi GW, et al. J Membr Biol. 1995 Sep;147(1):1-6. doi: 10.1007/BF00235393. J Membr Biol. 1995. PMID: 8531195
Nickel block of a family of neuronal calcium channels: subtype- and subunit-dependent action at multiple sites.
Zamponi GW, Bourinet E, Snutch TP. Zamponi GW, et al. J Membr Biol. 1996 May;151(1):77-90. doi: 10.1007/s002329900059. J Membr Biol. 1996. PMID: 8661496
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