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Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response.
Zuco V, Zanchi C, Lanzi C, Beretta GL, Supino R, Pisano C, Barbarino M, Zanier R, Bucci F, Aulicino C, Carminati P, Zunino F. Zuco V, et al. Among authors: zanier r. Neoplasia. 2005 Jul;7(7):667-77. doi: 10.1593/neo.05127. Neoplasia. 2005. PMID: 16026646 Free PMC article.
ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis.
Garattini E, Parrella E, Diomede L, Gianni' M, Kalac Y, Merlini L, Simoni D, Zanier R, Ferrara FF, Chiarucci I, Carminati P, Terao M, Pisano C. Garattini E, et al. Among authors: zanier r. Blood. 2004 Jan 1;103(1):194-207. doi: 10.1182/blood-2003-05-1577. Epub 2003 Sep 4. Blood. 2004. PMID: 12958071 Free article.