Zapp J - Search Results

1

Sulfation of the 3,4-methylenedioxymethamphetamine (MDMA) metabolites 3,4-dihydroxymethamphetamine (DHMA) and 4-hydroxy-3-methoxymethamphetamine (HMMA) and their capability to inhibit human sulfotransferases.

Schwaninger AE, Meyer MR, Zapp J, Maurer HH. Schwaninger AE, et al. Among authors: zapp j. Toxicol Lett. 2011 Apr 25;202(2):120-8. doi: 10.1016/j.toxlet.2011.01.026. Epub 2011 Feb 2. Toxicol Lett. 2011. PMID: 21295122

2

Biotechnological synthesis of the designer drug metabolite 4'-hydroxymethyl-alpha-pyrrolidinohexanophenone in fission yeast heterologously expressing human cytochrome P450 2D6--a versatile alternative to multistep chemical synthesis.

Peters FT, Dragan CA, Kauffels A, Schwaninger AE, Zapp J, Bureik M, Maurer HH. Peters FT, et al. Among authors: zapp j. J Anal Toxicol. 2009 May;33(4):190-7. doi: 10.1093/jat/33.4.190. J Anal Toxicol. 2009. PMID: 19470220

3

The role of human UDP-glucuronyltransferases on the formation of the methylenedioxymethamphetamine (ecstasy) phase II metabolites R- and S-3-methoxymethamphetamine 4-O-glucuronides.

Schwaninger AE, Meyer MR, Zapp J, Maurer HH. Schwaninger AE, et al. Among authors: zapp j. Drug Metab Dispos. 2009 Nov;37(11):2212-20. doi: 10.1124/dmd.109.029215. Epub 2009 Aug 10. Drug Metab Dispos. 2009. PMID: 19666989

4

Use of liquid chromatography coupled to low- and high-resolution linear ion trap mass spectrometry for studying the metabolism of paynantheine, an alkaloid of the herbal drug Kratom in rat and human urine.

Philipp AA, Wissenbach DK, Weber AA, Zapp J, Zoerntlein SW, Kanogsunthornrat J, Maurer HH. Philipp AA, et al. Among authors: zapp j. Anal Bioanal Chem. 2010 Apr;396(7):2379-91. doi: 10.1007/s00216-009-3239-1. Epub 2009 Nov 10. Anal Bioanal Chem. 2010. PMID: 19902190

5

Phase I and II metabolites of speciogynine, a diastereomer of the main Kratom alkaloid mitragynine, identified in rat and human urine by liquid chromatography coupled to low- and high-resolution linear ion trap mass spectrometry.

Philipp AA, Wissenbach DK, Weber AA, Zapp J, Maurer HH. Philipp AA, et al. Among authors: zapp j. J Mass Spectrom. 2010 Nov;45(11):1344-57. doi: 10.1002/jms.1848. Epub 2010 Oct 21. J Mass Spectrom. 2010. PMID: 20967737

6

Metabolism studies of the Kratom alkaloids mitraciliatine and isopaynantheine, diastereomers of the main alkaloids mitragynine and paynantheine, in rat and human urine using liquid chromatography-linear ion trap-mass spectrometry.

Philipp AA, Wissenbach DK, Weber AA, Zapp J, Maurer HH. Philipp AA, et al. Among authors: zapp j. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 May 1;879(15-16):1049-55. doi: 10.1016/j.jchromb.2011.03.005. Epub 2011 Mar 29. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21450536

7

Qualitative studies on the metabolism and the toxicological detection of the fentanyl-derived designer drugs 3-methylfentanyl and isofentanyl in rats using liquid chromatography-linear ion trap-mass spectrometry (LC-MS(n)).

Meyer MR, Dinger J, Schwaninger AE, Wissenbach DK, Zapp J, Fritschi G, Maurer HH. Meyer MR, et al. Among authors: zapp j. Anal Bioanal Chem. 2012 Jan;402(3):1249-55. doi: 10.1007/s00216-011-5528-8. Epub 2011 Nov 8. Anal Bioanal Chem. 2012. PMID: 22065349

8

Investigations on the stereoselectivity of the phase II metabolism of the 3,4-methylenedioxyethylamphetamine (MDEA) metabolites 3,4-dihydroxyethylamphetamine (DHEA) and 4-hydroxy-3-methoxyethylamphetamine (HMEA).

Schwaninger AE, Meyer MR, Zapp J, Maurer HH. Schwaninger AE, et al. Among authors: zapp j. Toxicol Lett. 2012 Jul 7;212(1):38-47. doi: 10.1016/j.toxlet.2012.04.021. Epub 2012 May 4. Toxicol Lett. 2012. PMID: 22564759

9

Studies on the in vivo contribution of human cytochrome P450s to the hepatic metabolism of glaucine, a new drug of abuse.

Meyer GM, Meyer MR, Wink CS, Zapp J, Maurer HH. Meyer GM, et al. Among authors: zapp j. Biochem Pharmacol. 2013 Nov 15;86(10):1497-506. doi: 10.1016/j.bcp.2013.08.025. Epub 2013 Aug 26. Biochem Pharmacol. 2013. PMID: 23988488

10

GC-MS, LC-MS(n), LC-high resolution-MS(n), and NMR studies on the metabolism and toxicological detection of mesembrine and mesembrenone, the main alkaloids of the legal high "Kanna" isolated from Sceletium tortuosum.

Meyer GM, Wink CS, Zapp J, Maurer HH. Meyer GM, et al. Among authors: zapp j. Anal Bioanal Chem. 2015 Jan;407(3):761-78. doi: 10.1007/s00216-014-8109-9. Epub 2014 Sep 21. Anal Bioanal Chem. 2015. PMID: 25240931

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