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38 results
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N-terminal isotope tagging strategy for quantitative proteomics: results-driven analysis of protein abundance changes.
Zappacosta F, Annan RS. Zappacosta F, et al. Anal Chem. 2004 Nov 15;76(22):6618-27. doi: 10.1021/ac049169b. Anal Chem. 2004. PMID: 15538785
Protein posttranslational modifications: phosphorylation site analysis using mass spectrometry.
Annan RS, Zappacosta F. Annan RS, et al. Among authors: zappacosta f. Methods Biochem Anal. 2005;45:85-106. Methods Biochem Anal. 2005. PMID: 19235292 Review. No abstract available.
An optimized platform for hydrophilic interaction chromatography-immobilized metal affinity chromatography enables deep coverage of the rat liver phosphoproteome.
Zappacosta F, Scott GF, Huddleston MJ, Annan RS. Zappacosta F, et al. J Proteome Res. 2015 Feb 6;14(2):997-1009. doi: 10.1021/pr501025e. Epub 2015 Jan 26. J Proteome Res. 2015. PMID: 25575281
A quantitative results-driven approach to analyzing multisite protein phosphorylation: the phosphate-dependent phosphorylation profile of the transcription factor Pho4.
Zappacosta F, Collingwood TS, Huddleston MJ, Annan RS. Zappacosta F, et al. Mol Cell Proteomics. 2006 Nov;5(11):2019-30. doi: 10.1074/mcp.M600238-MCP200. Epub 2006 Jul 6. Mol Cell Proteomics. 2006. PMID: 16825185
Improved sensitivity for phosphopeptide mapping using capillary column HPLC and microionspray mass spectrometry: comparative phosphorylation site mapping from gel-derived proteins.
Zappacosta F, Huddleston MJ, Karcher RL, Gelfand VI, Carr SA, Annan RS. Zappacosta F, et al. Anal Chem. 2002 Jul 1;74(13):3221-31. doi: 10.1021/ac025538x. Anal Chem. 2002. PMID: 12141686
Comparative phosphorylation site mapping from gel-derived proteins using a multidimensional ES/MS-based approach.
Zappacosta F, Huddleston MJ, Annan RS. Zappacosta F, et al. Methods Mol Biol. 2004;284:91-110. doi: 10.1385/1-59259-816-1:091. Methods Mol Biol. 2004. PMID: 15173611
The catalytic role of INCENP in Aurora B activation and the kinetic mechanism of Aurora B/INCENP.
Yang J, Zappacosta F, Annan RS, Nurse K, Tummino PJ, Copeland RA, Lai Z. Yang J, et al. Among authors: zappacosta f. Biochem J. 2009 Jan 1;417(1):355-60. doi: 10.1042/BJ20081365. Biochem J. 2009. PMID: 18767990
GSK1120212 (JTP-74057) is an inhibitor of MEK activity and activation with favorable pharmacokinetic properties for sustained in vivo pathway inhibition.
Gilmartin AG, Bleam MR, Groy A, Moss KG, Minthorn EA, Kulkarni SG, Rominger CM, Erskine S, Fisher KE, Yang J, Zappacosta F, Annan R, Sutton D, Laquerre SG. Gilmartin AG, et al. Among authors: zappacosta f. Clin Cancer Res. 2011 Mar 1;17(5):989-1000. doi: 10.1158/1078-0432.CCR-10-2200. Epub 2011 Jan 18. Clin Cancer Res. 2011. PMID: 21245089
Discovery and characterization of a cell-permeable, small-molecule c-Abl kinase activator that binds to the myristoyl binding site.
Yang J, Campobasso N, Biju MP, Fisher K, Pan XQ, Cottom J, Galbraith S, Ho T, Zhang H, Hong X, Ward P, Hofmann G, Siegfried B, Zappacosta F, Washio Y, Cao P, Qu J, Bertrand S, Wang DY, Head MS, Li H, Moores S, Lai Z, Johanson K, Burton G, Erickson-Miller C, Simpson G, Tummino P, Copeland RA, Oliff A. Yang J, et al. Among authors: zappacosta f. Chem Biol. 2011 Feb 25;18(2):177-86. doi: 10.1016/j.chembiol.2010.12.013. Chem Biol. 2011. PMID: 21338916
Structure-Based Design of a Novel SMYD3 Inhibitor that Bridges the SAM-and MEKK2-Binding Pockets.
Van Aller GS, Graves AP, Elkins PA, Bonnette WG, McDevitt PJ, Zappacosta F, Annan RS, Dean TW, Su DS, Carpenter CL, Mohammad HP, Kruger RG. Van Aller GS, et al. Among authors: zappacosta f. Structure. 2016 May 3;24(5):774-781. doi: 10.1016/j.str.2016.03.010. Epub 2016 Apr 7. Structure. 2016. PMID: 27066749 Free article.
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