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Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.
Aalto-Setälä K, Fisher EA, Chen X, Chajek-Shaul T, Hayek T, Zechner R, Walsh A, Ramakrishnan R, Ginsberg HN, Breslow JL. Aalto-Setälä K, et al. Among authors: zechner r. J Clin Invest. 1992 Nov;90(5):1889-900. doi: 10.1172/JCI116066. J Clin Invest. 1992. PMID: 1430212 Free PMC article.
Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes.
Weinstock PH, Bisgaier CL, Aalto-Setälä K, Radner H, Ramakrishnan R, Levak-Frank S, Essenburg AD, Zechner R, Breslow JL. Weinstock PH, et al. Among authors: zechner r. J Clin Invest. 1995 Dec;96(6):2555-68. doi: 10.1172/JCI118319. J Clin Invest. 1995. PMID: 8675619 Free PMC article.
Induced mutant mouse lines that express lipoprotein lipase in cardiac muscle, but not in skeletal muscle and adipose tissue, have normal plasma triglyceride and high-density lipoprotein-cholesterol levels.
Levak-Frank S, Hofmann W, Weinstock PH, Radner H, Sattler W, Breslow JL, Zechner R. Levak-Frank S, et al. Among authors: zechner r. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3165-70. doi: 10.1073/pnas.96.6.3165. Proc Natl Acad Sci U S A. 1999. PMID: 10077655 Free PMC article.
244 results