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XP13512 [(+/-)-1-([(alpha-isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane acetic acid], a novel gabapentin prodrug: I. Design, synthesis, enzymatic conversion to gabapentin, and transport by intestinal solute transporters.
Cundy KC, Branch R, Chernov-Rogan T, Dias T, Estrada T, Hold K, Koller K, Liu X, Mann A, Panuwat M, Raillard SP, Upadhyay S, Wu QQ, Xiang JN, Yan H, Zerangue N, Zhou CX, Barrett RW, Gallop MA. Cundy KC, et al. Among authors: zerangue n. J Pharmacol Exp Ther. 2004 Oct;311(1):315-23. doi: 10.1124/jpet.104.067934. Epub 2004 May 14. J Pharmacol Exp Ther. 2004. PMID: 15146028
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