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Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate.
Chen WH, Wei J, Kundu RT, Adhikari R, Liu Z, Lee J, Versteeg L, Poveda C, Keegan B, Villar MJ, de Araujo Leao AC, Rivera JA, Gillespie PM, Pollet J, Strych U, Zhan B, Hotez PJ, Bottazzi ME. Chen WH, et al. Among authors: zhan b. Biochim Biophys Acta Gen Subj. 2021 Jun;1865(6):129893. doi: 10.1016/j.bbagen.2021.129893. Epub 2021 Mar 14. Biochim Biophys Acta Gen Subj. 2021. PMID: 33731300 Free PMC article.
Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative.
Hotez PJ, Zhan B, Bethony JM, Loukas A, Williamson A, Goud GN, Hawdon JM, Dobardzic A, Dobardzic R, Ghosh K, Bottazzi ME, Mendez S, Zook B, Wang Y, Liu S, Essiet-Gibson I, Chung-Debose S, Xiao S, Knox D, Meagher M, Inan M, Correa-Oliveira R, Vilk P, Shepherd HR, Brandt W, Russell PK. Hotez PJ, et al. Among authors: zhan b. Int J Parasitol. 2003 Sep 30;33(11):1245-58. doi: 10.1016/s0020-7519(03)00158-9. Int J Parasitol. 2003. PMID: 13678639 Review.
Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum.
Goud GN, Zhan B, Ghosh K, Loukas A, Hawdon J, Dobardzic A, Deumic V, Liu S, Dobardzic R, Zook BC, Jin Q, Liu Y, Hoffman L, Chung-Debose S, Patel R, Mendez S, Hotez PJ. Goud GN, et al. Among authors: zhan b. J Infect Dis. 2004 Mar 1;189(5):919-29. doi: 10.1086/381901. Epub 2004 Feb 6. J Infect Dis. 2004. PMID: 14976610
Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum.
Mendez S, Zhan B, Goud G, Ghosh K, Dobardzic A, Wu W, Liu S, Deumic V, Dobardzic R, Liu Y, Bethony J, Hotez PJ. Mendez S, et al. Among authors: zhan b. Vaccine. 2005 May 2;23(24):3123-30. doi: 10.1016/j.vaccine.2004.12.022. Vaccine. 2005. PMID: 15837211
Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals.
Bethony J, Loukas A, Smout M, Brooker S, Mendez S, Plieskatt J, Goud G, Bottazzi ME, Zhan B, Wang Y, Williamson A, Lustigman S, Correa-Oliveira R, Xiao S, Hotez PJ. Bethony J, et al. Among authors: zhan b. FASEB J. 2005 Oct;19(12):1743-5. doi: 10.1096/fj.05-3936fje. Epub 2005 Jul 21. FASEB J. 2005. PMID: 16037096
Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials.
Goud GN, Bottazzi ME, Zhan B, Mendez S, Deumic V, Plieskatt J, Liu S, Wang Y, Bueno L, Fujiwara R, Samuel A, Ahn SY, Solanki M, Asojo OA, Wang J, Bethony JM, Loukas A, Roy M, Hotez PJ. Goud GN, et al. Among authors: zhan b. Vaccine. 2005 Sep 15;23(39):4754-64. doi: 10.1016/j.vaccine.2005.04.040. Vaccine. 2005. PMID: 16054275
460 results