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244-MPT overcomes gefitinib resistance in non-small cell lung cancer cells.
Zhang Y, Yao K, Shi C, Jiang Y, Liu K, Zhao S, Chen H, Reddy K, Zhang C, Chang X, Ryu J, Bode AM, Dong Z, Dong Z. Zhang Y, et al. Among authors: zhang c. Oncotarget. 2015 Dec 29;6(42):44274-88. doi: 10.18632/oncotarget.6236. Oncotarget. 2015. PMID: 26517520 Free PMC article.
S-15 in combination of Akt inhibitor promotes the expansion of CD45RA-CCR7+ tumor infiltrating lymphocytes with high cytotoxic potential and downregulating PD-1+Tim-3+ cells as well as regulatory T cells.
Xu B, Yuan L, Chen G, Li T, Zhou J, Zhang C, Qin P, Muthana MM, Wang S, Du X, Gao Q. Xu B, et al. Among authors: zhang c. Cancer Cell Int. 2019 Dec 3;19:322. doi: 10.1186/s12935-019-1043-3. eCollection 2019. Cancer Cell Int. 2019. PMID: 31827396 Free PMC article.
CDK12 and PAK2 as novel therapeutic targets for human gastric cancer.
Liu H, Shin SH, Chen H, Liu T, Li Z, Hu Y, Liu F, Zhang C, Kim DJ, Liu K, Dong Z. Liu H, et al. Among authors: zhang c. Theranostics. 2020 May 15;10(14):6201-6215. doi: 10.7150/thno.46137. eCollection 2020. Theranostics. 2020. PMID: 32483448 Free PMC article.
IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor.
Liu Y, Zhou N, Zhou L, Wang J, Zhou Y, Zhang T, Fang Y, Deng J, Gao Y, Liang X, Lv J, Wang Z, Xie J, Xue Y, Zhang H, Ma J, Tang K, Fang Y, Cheng F, Zhang C, Dong B, Zhao Y, Yuan P, Gao Q, Zhang H, Xiao-Feng Qin F, Huang B. Liu Y, et al. Among authors: zhang c, zhang t, zhang h. Nat Immunol. 2021 Mar;22(3):358-369. doi: 10.1038/s41590-020-00850-9. Epub 2021 Jan 11. Nat Immunol. 2021. PMID: 33432230
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