Zhang F - Search Results

1

Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir.

Xia Z, Sacco M, Hu Y, Ma C, Meng X, Zhang F, Szeto T, Xiang Y, Chen Y, Wang J. Xia Z, et al. Among authors: zhang f. ACS Pharmacol Transl Sci. 2021 Jun 9;4(4):1408-1421. doi: 10.1021/acsptsci.1c00099. eCollection 2021 Aug 13. ACS Pharmacol Transl Sci. 2021. PMID: 34414360 Free PMC article.

2

A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection.

Meng X, Zhang F, Yan B, Si C, Honda H, Nagamachi A, Sun LZ, Xiang Y. Meng X, et al. Among authors: zhang f. PLoS Pathog. 2018 Feb 15;14(2):e1006884. doi: 10.1371/journal.ppat.1006884. eCollection 2018 Feb. PLoS Pathog. 2018. PMID: 29447249 Free PMC article.

3

Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer.

Pathak PK, Peng S, Meng X, Han Y, Zhang B, Zhang F, Xiang Y, Deng J. Pathak PK, et al. Among authors: zhang b, zhang f. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7028-7032. doi: 10.1073/pnas.1805855115. Epub 2018 Jun 18. Proc Natl Acad Sci U S A. 2018. PMID: 29915071 Free PMC article.

4

Identification of CP77 as the Third Orthopoxvirus SAMD9 and SAMD9L Inhibitor with Unique Specificity for a Rodent SAMD9L.

Zhang F, Meng X, Townsend MB, Satheshkumar PS, Xiang Y. Zhang F, et al. J Virol. 2019 May 29;93(12):e00225-19. doi: 10.1128/JVI.00225-19. Print 2019 Jun 15. J Virol. 2019. PMID: 30918078 Free PMC article.

5

Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness.

She L, Alanazi HH, Yan L, Brooks EG, Dube PH, Xiang Y, Zhang F, Sun Y, Liu Y, Zhang X, Li XD. She L, et al. Among authors: zhang f, zhang x. PLoS One. 2020 Jul 30;15(7):e0236744. doi: 10.1371/journal.pone.0236744. eCollection 2020. PLoS One. 2020. PMID: 32730309 Free PMC article.

6

The in vitro antiviral activity of lactoferrin against common human coronaviruses and SARS-CoV-2 is mediated by targeting the heparan sulfate co-receptor.

Hu Y, Meng X, Zhang F, Xiang Y, Wang J. Hu Y, et al. Among authors: zhang f. Emerg Microbes Infect. 2021 Dec;10(1):317-330. doi: 10.1080/22221751.2021.1888660. Emerg Microbes Infect. 2021. PMID: 33560940 Free PMC article.

7

Expedited Approach toward the Rational Design of Noncovalent SARS-CoV-2 Main Protease Inhibitors.

Kitamura N, Sacco MD, Ma C, Hu Y, Townsend JA, Meng X, Zhang F, Zhang X, Ba M, Szeto T, Kukuljac A, Marty MT, Schultz D, Cherry S, Xiang Y, Chen Y, Wang J. Kitamura N, et al. Among authors: zhang f, zhang x. J Med Chem. 2022 Feb 24;65(4):2848-2865. doi: 10.1021/acs.jmedchem.1c00509. Epub 2021 Apr 23. J Med Chem. 2022. PMID: 33891389 Free PMC article.

8

Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay.

Ma C, Sacco MD, Xia Z, Lambrinidis G, Townsend JA, Hu Y, Meng X, Szeto T, Ba M, Zhang X, Gongora M, Zhang F, Marty MT, Xiang Y, Kolocouris A, Chen Y, Wang J. Ma C, et al. Among authors: zhang f, zhang x. ACS Cent Sci. 2021 Jul 28;7(7):1245-1260. doi: 10.1021/acscentsci.1c00519. Epub 2021 Jun 18. ACS Cent Sci. 2021. PMID: 34341772 Free PMC article.

9

Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity.

Ma C, Xia Z, Sacco MD, Hu Y, Townsend JA, Meng X, Choza J, Tan H, Jang J, Gongora MV, Zhang X, Zhang F, Xiang Y, Marty MT, Chen Y, Wang J. Ma C, et al. Among authors: zhang f, zhang x. J Am Chem Soc. 2021 Dec 15;143(49):20697-20709. doi: 10.1021/jacs.1c08060. Epub 2021 Dec 3. J Am Chem Soc. 2021. PMID: 34860011 Free PMC article.

10

Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SAMD9L.

Peng S, Meng X, Zhang F, Pathak PK, Chaturvedi J, Coronado J, Morales M, Mao Y, Qian SB, Deng J, Xiang Y. Peng S, et al. Among authors: zhang f. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2116550119. doi: 10.1073/pnas.2116550119. Proc Natl Acad Sci U S A. 2022. PMID: 35046037 Free PMC article.

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