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Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition.
Zhang H, Cohen AL, Krishnakumar S, Wapnir IL, Veeriah S, Deng G, Coram MA, Piskun CM, Longacre TA, Herrler M, Frimannsson DO, Telli ML, Dirbas FM, Matin AC, Dairkee SH, Larijani B, Glinsky GV, Bild AH, Jeffrey SS. Zhang H, et al. Breast Cancer Res. 2014 Apr 7;16(2):R36. doi: 10.1186/bcr3640. Breast Cancer Res. 2014. PMID: 24708766 Free PMC article.
Single cell mutational analysis of PIK3CA in circulating tumor cells and metastases in breast cancer reveals heterogeneity, discordance, and mutation persistence in cultured disseminated tumor cells from bone marrow.
Deng G, Krishnakumar S, Powell AA, Zhang H, Mindrinos MN, Telli ML, Davis RW, Jeffrey SS. Deng G, et al. Among authors: zhang h. BMC Cancer. 2014 Jun 19;14:456. doi: 10.1186/1471-2407-14-456. BMC Cancer. 2014. PMID: 24947048 Free PMC article.
Investigating circulating tumor cells and distant metastases in patient-derived orthotopic xenograft models of triple-negative breast cancer.
Ramani VC, Lemaire CA, Triboulet M, Casey KM, Heirich K, Renier C, Vilches-Moure JG, Gupta R, Razmara AM, Zhang H, Sledge GW, Sollier E, Jeffrey SS. Ramani VC, et al. Among authors: zhang h. Breast Cancer Res. 2019 Aug 28;21(1):98. doi: 10.1186/s13058-019-1182-4. Breast Cancer Res. 2019. PMID: 31462307 Free PMC article.
A pharmacogenomic method for individualized prediction of drug sensitivity.
Cohen AL, Soldi R, Zhang H, Gustafson AM, Wilcox R, Welm BE, Chang JT, Johnson E, Spira A, Jeffrey SS, Bild AH. Cohen AL, et al. Among authors: zhang h. Mol Syst Biol. 2011 Jul 19;7:513. doi: 10.1038/msb.2011.47. Mol Syst Biol. 2011. PMID: 21772261 Free PMC article.
Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines.
Powell AA, Talasaz AH, Zhang H, Coram MA, Reddy A, Deng G, Telli ML, Advani RH, Carlson RW, Mollick JA, Sheth S, Kurian AW, Ford JM, Stockdale FE, Quake SR, Pease RF, Mindrinos MN, Bhanot G, Dairkee SH, Davis RW, Jeffrey SS. Powell AA, et al. Among authors: zhang h. PLoS One. 2012;7(5):e33788. doi: 10.1371/journal.pone.0033788. Epub 2012 May 7. PLoS One. 2012. PMID: 22586443 Free PMC article.
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