Zhang J - Search Results

1

Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol.

Wang L, Smith J, Breton C, Clark P, Zhang J, Ying L, Che Y, Lape J, Bell P, Calcedo R, Buza EL, Saveliev A, Bartsevich VV, He Z, White J, Li M, Jantz D, Wilson JM. Wang L, et al. Among authors: zhang j. Nat Biotechnol. 2018 Sep;36(8):717-725. doi: 10.1038/nbt.4182. Epub 2018 Jul 9. Nat Biotechnol. 2018. PMID: 29985478

2

CRISPR/Cas9-mediated in vivo gene targeting corrects hemostasis in newborn and adult factor IX-knockout mice.

Wang L, Yang Y, Breton CA, White J, Zhang J, Che Y, Saveliev A, McMenamin D, He Z, Latshaw C, Li M, Wilson JM. Wang L, et al. Among authors: zhang j. Blood. 2019 Jun 27;133(26):2745-2752. doi: 10.1182/blood.2019000790. Epub 2019 Apr 11. Blood. 2019. PMID: 30975639 Free article.

3

Accurate and Rapid Sequence Analysis of Adeno-Associated Virus Plasmids by Illumina Next-Generation Sequencing.

Saveliev A, Liu J, Li M, Hirata L, Latshaw C, Zhang J, Wilson JM. Saveliev A, et al. Among authors: zhang j. Hum Gene Ther Methods. 2018 Oct;29(5):201-211. doi: 10.1089/hgtb.2018.037. Epub 2018 Aug 22. Hum Gene Ther Methods. 2018. PMID: 30051733

4

A mutation-independent CRISPR-Cas9-mediated gene targeting approach to treat a murine model of ornithine transcarbamylase deficiency.

Wang L, Yang Y, Breton C, Bell P, Li M, Zhang J, Che Y, Saveliev A, He Z, White J, Latshaw C, Xu C, McMenamin D, Yu H, Morizono H, Batshaw ML, Wilson JM. Wang L, et al. Among authors: zhang j. Sci Adv. 2020 Feb 12;6(7):eaax5701. doi: 10.1126/sciadv.aax5701. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32095520 Free PMC article.

5

Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in Mice.

Ferreira MJ, McKenna LB, Zhang J, Reichert M, Bakir B, Buza EL, Furth EE, Bogue CW, Rustgi AK, Kaestner KH. Ferreira MJ, et al. Among authors: zhang j. Cell Mol Gastroenterol Hepatol. 2015 Sep 1;1(5):550-569. doi: 10.1016/j.jcmgh.2015.06.007. Cell Mol Gastroenterol Hepatol. 2015. PMID: 26740970 Free PMC article.

6

The diabetes gene Hhex maintains δ-cell differentiation and islet function.

Zhang J, McKenna LB, Bogue CW, Kaestner KH. Zhang J, et al. Genes Dev. 2014 Apr 15;28(8):829-34. doi: 10.1101/gad.235499.113. Genes Dev. 2014. PMID: 24736842 Free PMC article.

7

Epigenetic Analysis of Endocrine Cell Subtypes from Human Pancreatic Islets.

Zhang J, Kaestner KH. Zhang J, et al. Methods Mol Biol. 2017;1507:95-111. doi: 10.1007/978-1-4939-6518-2_8. Methods Mol Biol. 2017. PMID: 27832535

8

High-fidelity Glucagon-CreER mouse line generated by CRISPR-Cas9 assisted gene targeting.

Ackermann AM, Zhang J, Heller A, Briker A, Kaestner KH. Ackermann AM, et al. Among authors: zhang j. Mol Metab. 2017 Jan 12;6(3):236-244. doi: 10.1016/j.molmet.2017.01.003. eCollection 2017 Mar. Mol Metab. 2017. PMID: 28271030 Free PMC article.

9

Overexpression of ST5, an activator of Ras, has no effect on β-cell proliferation in adult mice.

Ou K, Zhang J, Jiao Y, Wang ZV, Scherer P, Kaestner KH. Ou K, et al. Among authors: zhang j. Mol Metab. 2018 May;11:212-217. doi: 10.1016/j.molmet.2018.03.009. Epub 2018 Mar 23. Mol Metab. 2018. PMID: 29650351 Free PMC article.

10

Overexpression of hepatocyte nuclear factor-4α initiates cell cycle entry, but is not sufficient to promote β-cell expansion in human islets.

Rieck S, Zhang J, Li Z, Liu C, Naji A, Takane KK, Fiaschi-Taesch NM, Stewart AF, Kushner JA, Kaestner KH. Rieck S, et al. Among authors: zhang j. Mol Endocrinol. 2012 Sep;26(9):1590-602. doi: 10.1210/me.2012-1019. Epub 2012 Jul 13. Mol Endocrinol. 2012. PMID: 22798294 Free PMC article.

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