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Dendritic cells, engineered to overexpress 25-hydroxyvitamin D 1α-hydroxylase and pulsed with a myelin antigen, provide myelin-specific suppression of ongoing experimental allergic encephalomyelitis.
Li CH, Zhang J, Baylink DJ, Wang X, Goparaju NB, Xu Y, Wasnik S, Cheng Y, Berumen EC, Qin X, Lau KW, Tang X. Li CH, et al. Among authors: zhang j. FASEB J. 2017 Jul;31(7):2996-3006. doi: 10.1096/fj.201601243R. Epub 2017 Mar 31. FASEB J. 2017. PMID: 28363955 Free PMC article.
Our data support a novel concept that immunogenic DCs can be engineered for myelin-specific therapy for MS.-Li, C.-H., Zhang, J., Baylink, D. J., Wang, X., Goparaju, N. B., Xu, Y., Wasnik, S., Cheng, Y., Berumen, E. ...
Our data support a novel concept that immunogenic DCs can be engineered for myelin-specific therapy for MS.-Li, C.-H., Zhang, J …
In Vivo Generation of Gut-Homing Regulatory T Cells for the Suppression of Colitis.
Xu Y, Cheng Y, Baylink DJ, Wasnik S, Goel G, Huang M, Cao H, Qin X, Lau KW, Chan C, Koch A, Pham LH, Zhang J, Li CH, Wang X, Berumen EC, Smith J, Tang X. Xu Y, et al. Among authors: zhang j. J Immunol. 2019 Jun 15;202(12):3447-3457. doi: 10.4049/jimmunol.1800018. Epub 2019 May 3. J Immunol. 2019. PMID: 31053627 Free PMC article.
Gene replacement therapy in Bietti crystalline corneoretinal dystrophy: an open-label, single-arm, exploratory trial.
Wang J, Zhang J, Yu S, Li H, Chen S, Luo J, Wang H, Guan Y, Zhang H, Yin S, Wang H, Li H, Liu J, Zhu J, Yang Q, Sha Y, Zhang C, Yang Y, Yang X, Zhang X, Zhao X, Wang L, Yang L, Wei W. Wang J, et al. Among authors: zhang j. Signal Transduct Target Ther. 2024 Apr 24;9(1):95. doi: 10.1038/s41392-024-01806-3. Signal Transduct Target Ther. 2024. PMID: 38653979
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