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Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening.
Gutbier S, Wanke F, Dahm N, Rümmelin A, Zimmermann S, Christensen K, Köchl F, Rautanen A, Hatje K, Geering B, Zhang JD, Britschgi M, Cowley SA, Patsch C. Gutbier S, et al. Among authors: zhang jd. Int J Mol Sci. 2020 Jul 7;21(13):4808. doi: 10.3390/ijms21134808. Int J Mol Sci. 2020. PMID: 32645954 Free PMC article.
Detect tissue heterogeneity in gene expression data with BioQC.
Zhang JD, Hatje K, Sturm G, Broger C, Ebeling M, Burtin M, Terzi F, Pomposiello SI, Badi L. Zhang JD, et al. BMC Genomics. 2017 Apr 4;18(1):277. doi: 10.1186/s12864-017-3661-2. BMC Genomics. 2017. PMID: 28376718 Free PMC article.
Modeling the Effects of Severe Metabolic Disease by Genome Editing of hPSC-Derived Endothelial Cells Reveals an Inflammatory Phenotype.
Roudnicky F, Lan Y, Friesen M, Dernick G, Zhang JD, Staempfli A, Bordag N, Wagner-Golbs A, Christensen K, Ebeling M, Graf M, Burcin M, Meyer CA, Cowan CA, Patsch C. Roudnicky F, et al. Among authors: zhang jd. Int J Mol Sci. 2019 Dec 9;20(24):6201. doi: 10.3390/ijms20246201. Int J Mol Sci. 2019. PMID: 31835296 Free PMC article.
Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells.
Roudnicky F, Zhang JD, Kim BK, Pandya NJ, Lan Y, Sach-Peltason L, Ragelle H, Strassburger P, Gruener S, Lazendic M, Uhles S, Revelant F, Eidam O, Sturm G, Kueppers V, Christensen K, Goldstein LD, Tzouros M, Banfai B, Modrusan Z, Graf M, Patsch C, Burcin M, Meyer CA, Westenskow PD, Cowan CA. Roudnicky F, et al. Among authors: zhang jd. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):19854-19865. doi: 10.1073/pnas.1911532117. Epub 2020 Aug 5. Proc Natl Acad Sci U S A. 2020. PMID: 32759214 Free PMC article.
Besca, a single-cell transcriptomics analysis toolkit to accelerate translational research.
Mädler SC, Julien-Laferriere A, Wyss L, Phan M, Sonrel A, Kang ASW, Ulrich E, Schmucki R, Zhang JD, Ebeling M, Badi L, Kam-Thong T, Schwalie PC, Hatje K. Mädler SC, et al. Among authors: zhang jd. NAR Genom Bioinform. 2021 Nov 8;3(4):lqab102. doi: 10.1093/nargab/lqab102. eCollection 2021 Dec. NAR Genom Bioinform. 2021. PMID: 34761219 Free PMC article.
Optimization of the TeraTox Assay for Preclinical Teratogenicity Assessment.
Jaklin M, Zhang JD, Schäfer N, Clemann N, Barrow P, Küng E, Sach-Peltason L, McGinnis C, Leist M, Kustermann S. Jaklin M, et al. Among authors: zhang jd. Toxicol Sci. 2022 Jun 28;188(1):17-33. doi: 10.1093/toxsci/kfac046. Toxicol Sci. 2022. PMID: 35485993 Free PMC article.
Molecular Phenotyping Combines Molecular Information, Biological Relevance, and Patient Data to Improve Productivity of Early Drug Discovery.
Drawnel FM, Zhang JD, Küng E, Aoyama N, Benmansour F, Araujo Del Rosario A, Jensen Zoffmann S, Delobel F, Prummer M, Weibel F, Carlson C, Anson B, Iacone R, Certa U, Singer T, Ebeling M, Prunotto M. Drawnel FM, et al. Among authors: zhang jd. Cell Chem Biol. 2017 May 18;24(5):624-634.e3. doi: 10.1016/j.chembiol.2017.03.016. Epub 2017 Apr 20. Cell Chem Biol. 2017. PMID: 28434878 Free article.
440 results