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Angiotensin-converting enzyme 2 is an essential regulator of heart function.
Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, da Costa J, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y, Penninger JM. Crackower MA, et al. Among authors: zhang l. Nature. 2002 Jun 20;417(6891):822-8. doi: 10.1038/nature00786. Nature. 2002. PMID: 12075344
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.
Neely GG, Kuba K, Cammarato A, Isobe K, Amann S, Zhang L, Murata M, Elmén L, Gupta V, Arora S, Sarangi R, Dan D, Fujisawa S, Usami T, Xia CP, Keene AC, Alayari NN, Yamakawa H, Elling U, Berger C, Novatchkova M, Koglgruber R, Fukuda K, Nishina H, Isobe M, Pospisilik JA, Imai Y, Pfeufer A, Hicks AA, Pramstaller PP, Subramaniam S, Kimura A, Ocorr K, Bodmer R, Penninger JM. Neely GG, et al. Among authors: zhang l. Cell. 2010 Apr 2;141(1):142-53. doi: 10.1016/j.cell.2010.02.023. Cell. 2010. PMID: 20371351 Free PMC article.
Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload.
Kuba K, Zhang L, Imai Y, Arab S, Chen M, Maekawa Y, Leschnik M, Leibbrandt A, Markovic M, Schwaighofer J, Beetz N, Musialek R, Neely GG, Komnenovic V, Kolm U, Metzler B, Ricci R, Hara H, Meixner A, Nghiem M, Chen X, Dawood F, Wong KM, Sarao R, Cukerman E, Kimura A, Hein L, Thalhammer J, Liu PP, Penninger JM. Kuba K, et al. Among authors: zhang l. Circ Res. 2007 Aug 17;101(4):e32-42. doi: 10.1161/CIRCRESAHA.107.158659. Epub 2007 Aug 2. Circ Res. 2007. PMID: 17673668
Metformin increases degradation of phospholamban via autophagy in cardiomyocytes.
Teng AC, Miyake T, Yokoe S, Zhang L, Rezende LM Jr, Sharma P, MacLennan DH, Liu PP, Gramolini AO. Teng AC, et al. Among authors: zhang l. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7165-70. doi: 10.1073/pnas.1508815112. Epub 2015 May 26. Proc Natl Acad Sci U S A. 2015. PMID: 26040000 Free PMC article.
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