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75,001 results
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Mechanisms of resistance to TRAIL-induced apoptosis in cancer.
Zhang L, Fang B. Zhang L, et al. Cancer Gene Ther. 2005 Mar;12(3):228-37. doi: 10.1038/sj.cgt.7700792. Cancer Gene Ther. 2005. PMID: 15550937 Review.
Overexpression of Bcl-2 or Bcl-X(L), loss of Bax or Bak function, high expression of inhibitor of apoptosis proteins, and reduced release of second mitochondria-derived activator of caspases (Smac/Diablo) from the mitochondria to the cytosol have all been reported to resul …
Overexpression of Bcl-2 or Bcl-X(L), loss of Bax or Bak function, high expression of inhibitor of apoptosis proteins, and reduced rel …
Roles and mechanisms of microRNAs in pancreatic cancer.
Zhang L, Jamaluddin MS, Weakley SM, Yao Q, Chen C. Zhang L, et al. World J Surg. 2011 Aug;35(8):1725-31. doi: 10.1007/s00268-010-0952-z. World J Surg. 2011. PMID: 21222121 Free PMC article. Review.
Characterization of bortezomib-adapted I-45 mesothelioma cells.
Zhang L, Littlejohn JE, Cui Y, Cao X, Peddaboina C, Smythe WR. Zhang L, et al. Mol Cancer. 2010 May 18;9:110. doi: 10.1186/1476-4598-9-110. Mol Cancer. 2010. PMID: 20482802 Free PMC article.
Bcl2/bcl-xL inhibitor engenders apoptosis and increases chemosensitivity in mesothelioma.
Cao X, Rodarte C, Zhang L, Morgan CD, Littlejohn J, Smythe WR. Cao X, et al. Cancer Biol Ther. 2007 Feb;6(2):246-52. doi: 10.4161/cbt.6.2.3626. Epub 2007 Feb 26. Cancer Biol Ther. 2007. PMID: 17224645 Clinical Trial.
Previously, we demonstrated that mesothelioma overexpresses BCL-X(L), an anti-apoptotic member of the BCL-2 family. In addition, we have shown that down regulation of BCL-X(L) using a BCL-X(L) antisense oligonucleotide engenders mesothelioma apoptotic cell de …
Previously, we demonstrated that mesothelioma overexpresses BCL-X(L), an anti-apoptotic member of the BCL-2 family. In addition, we h …
Downregulation of XIAP and induction of apoptosis by the synthetic cyclin-dependent kinase inhibitor GW8510 in non-small cell lung cancer cells.
Dong F, Guo W, Zhang L, Wu S, Teraishi F, Davis JJ, Fang B. Dong F, et al. Cancer Biol Ther. 2006 Feb;5(2):165-70. doi: 10.4161/cbt.5.2.2316. Epub 2006 Feb 10. Cancer Biol Ther. 2006. PMID: 16322690
Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
Zhu H, Guo W, Zhang L, Wu S, Teraishi F, Davis JJ, Dong F, Fang B. Zhu H, et al. Cancer Biol Ther. 2005 Jul;4(7):781-6. doi: 10.4161/cbt.4.7.1897. Epub 2005 Jul 6. Cancer Biol Ther. 2005. PMID: 16082182 Free PMC article.
Eliminating established tumor in nu/nu nude mice by a tumor necrosis factor-alpha-related apoptosis-inducing ligand-armed oncolytic adenovirus.
Dong F, Wang L, Davis JJ, Hu W, Zhang L, Guo W, Teraishi F, Ji L, Fang B. Dong F, et al. Clin Cancer Res. 2006 Sep 1;12(17):5224-30. doi: 10.1158/1078-0432.CCR-06-0244. Clin Cancer Res. 2006. PMID: 16951242 Free PMC article.
Activation of sterile20-like kinase 1 in proteasome inhibitor bortezomib-induced apoptosis in oncogenic K-ras-transformed cells.
Teraishi F, Guo W, Zhang L, Dong F, Davis JJ, Sasazuki T, Shirasawa S, Liu J, Fang B. Teraishi F, et al. Cancer Res. 2006 Jun 15;66(12):6072-9. doi: 10.1158/0008-5472.CAN-06-0125. Cancer Res. 2006. PMID: 16778179 Free PMC article.
Activation of c-Jun NH2-terminal kinase is required for gemcitabine's cytotoxic effect in human lung cancer H1299 cells.
Teraishi F, Zhang L, Guo W, Dong F, Davis JJ, Lin A, Fang B. Teraishi F, et al. FEBS Lett. 2005 Dec 5;579(29):6681-7. doi: 10.1016/j.febslet.2005.10.064. Epub 2005 Nov 14. FEBS Lett. 2005. PMID: 16307741 Free PMC article.
Antitumor activity and downregulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound.
Teraishi F, Wu S, Inoue S, Zhang L, Davis JJ, Guo W, Dong F, Fang B. Teraishi F, et al. Prostate. 2006 Mar 1;66(4):430-8. doi: 10.1002/pros.20373. Prostate. 2006. PMID: 16302260 Free PMC article.
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