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Metabolic profiling of hearts exposed to sevoflurane and propofol reveals distinct regulation of fatty acid and glucose oxidation: CD36 and pyruvate dehydrogenase as key regulators in anesthetic-induced fuel shift.
Wang L, Ko KW, Lucchinetti E, Zhang L, Troxler H, Hersberger M, Omar MA, Posse de Chaves EI, Lopaschuk GD, Clanachan AS, Zaugg M. Wang L, et al. Among authors: zhang l. Anesthesiology. 2010 Sep;113(3):541-51. doi: 10.1097/ALN.0b013e3181e2c1a1. Anesthesiology. 2010. PMID: 20683255 Free article.
The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases.
Lou PH, Lucchinetti E, Zhang L, Affolter A, Schaub MC, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi HF, Clanachan AS, Zaugg M. Lou PH, et al. Among authors: zhang l. PLoS One. 2014 Jan 30;9(1):e87205. doi: 10.1371/journal.pone.0087205. eCollection 2014. PLoS One. 2014. PMID: 24498043 Free PMC article.
Agonist-induced hypertrophy and diastolic dysfunction are associated with selective reduction in glucose oxidation: a metabolic contribution to heart failure with normal ejection fraction.
Mori J, Basu R, McLean BA, Das SK, Zhang L, Patel VB, Wagg CS, Kassiri Z, Lopaschuk GD, Oudit GY. Mori J, et al. Among authors: zhang l. Circ Heart Fail. 2012 Jul 1;5(4):493-503. doi: 10.1161/CIRCHEARTFAILURE.112.966705. Epub 2012 Jun 15. Circ Heart Fail. 2012. PMID: 22705769
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