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63,812 results

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Page 1
Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia.
Wang DH, Tiwari A, Kim ME, Clemons NJ, Regmi NL, Hodges WA, Berman DM, Montgomery EA, Watkins DN, Zhang X, Zhang Q, Jie C, Spechler SJ, Souza RF. Wang DH, et al. Among authors: zhang q, zhang x. J Clin Invest. 2014 Sep;124(9):3767-80. doi: 10.1172/JCI66603. Epub 2014 Aug 1. J Clin Invest. 2014. PMID: 25083987 Free PMC article.
Cancer-related inflammation and Barrett's carcinogenesis: interleukin-6 and STAT3 mediate apoptotic resistance in transformed Barrett's cells.
Zhang HY, Zhang Q, Zhang X, Yu C, Huo X, Cheng E, Wang DH, Spechler SJ, Souza RF. Zhang HY, et al. Among authors: zhang q, zhang x. Am J Physiol Gastrointest Liver Physiol. 2011 Mar;300(3):G454-60. doi: 10.1152/ajpgi.00458.2010. Epub 2010 Dec 9. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21148399 Free PMC article.
Deoxycholic acid causes DNA damage while inducing apoptotic resistance through NF-κB activation in benign Barrett's epithelial cells.
Huo X, Juergens S, Zhang X, Rezaei D, Yu C, Strauch ED, Wang JY, Cheng E, Meyer F, Wang DH, Zhang Q, Spechler SJ, Souza RF. Huo X, et al. Among authors: zhang q, zhang x. Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G278-86. doi: 10.1152/ajpgi.00092.2011. Epub 2011 Jun 2. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21636532 Free PMC article.
Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells.
Yu C, Zhang Q, Zhang HY, Zhang X, Huo X, Cheng E, Wang DH, Arbiser JL, Spechler SJ, Souza RF. Yu C, et al. Among authors: zhang q, zhang x, zhang hy. Am J Physiol Gastrointest Liver Physiol. 2012 Sep 1;303(5):G561-9. doi: 10.1152/ajpgi.00033.2012. Epub 2012 Jun 28. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22744336 Free PMC article.
Autocrine VEGF signaling promotes proliferation of neoplastic Barrett's epithelial cells through a PLC-dependent pathway.
Zhang Q, Yu C, Peng S, Xu H, Wright E, Zhang X, Huo X, Cheng E, Pham TH, Asanuma K, Hatanpaa KJ, Rezai D, Wang DH, Sarode V, Melton S, Genta RM, Spechler SJ, Souza RF. Zhang Q, et al. Among authors: zhang x. Gastroenterology. 2014 Feb;146(2):461-72.e6. doi: 10.1053/j.gastro.2013.10.011. Epub 2013 Oct 9. Gastroenterology. 2014. PMID: 24120473 Free PMC article.
In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids.
Peng S, Huo X, Rezaei D, Zhang Q, Zhang X, Yu C, Asanuma K, Cheng E, Pham TH, Wang DH, Chen M, Souza RF, Spechler SJ. Peng S, et al. Among authors: zhang q, zhang x. Am J Physiol Gastrointest Liver Physiol. 2014 Jul 15;307(2):G129-39. doi: 10.1152/ajpgi.00085.2014. Epub 2014 May 22. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 24852569 Free PMC article. Clinical Trial.
In oesophageal squamous cells, nitric oxide causes S-nitrosylation of Akt and blocks SOX2 (sex determining region Y-box 2) expression.
Asanuma K, Huo X, Agoston A, Zhang X, Yu C, Cheng E, Zhang Q, Dunbar KB, Pham TH, Wang DH, Iijima K, Shimosegawa T, Odze RD, Spechler SJ, Souza RF. Asanuma K, et al. Among authors: zhang q, zhang x. Gut. 2016 Sep;65(9):1416-26. doi: 10.1136/gutjnl-2015-309272. Epub 2015 May 18. Gut. 2016. PMID: 25986942 Free PMC article.
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