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RNA m6A regulates transcription via DNA demethylation and chromatin accessibility.
Deng S, Zhang J, Su J, Zuo Z, Zeng L, Liu K, Zheng Y, Huang X, Bai R, Zhuang L, Ye Y, Li M, Pan L, Deng J, Wu G, Li R, Zhang S, Wu C, Lin D, Chen J, Zheng J. Deng S, et al. Among authors: zhang s, zhang j. Nat Genet. 2022 Sep;54(9):1427-1437. doi: 10.1038/s41588-022-01173-1. Epub 2022 Sep 7. Nat Genet. 2022. PMID: 36071173
LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling.
Huang X, Pan L, Zuo Z, Li M, Zeng L, Li R, Ye Y, Zhang J, Wu G, Bai R, Zhuang L, Wei L, Zheng Y, Su J, Deng J, Deng S, Zhang S, Zhu S, Che X, Wang C, Wu C, Chen R, Lin D, Zheng J. Huang X, et al. Among authors: zhang s, zhang j. Nat Commun. 2021 Jun 22;12(1):3830. doi: 10.1038/s41467-021-23904-4. Nat Commun. 2021. PMID: 34158490 Free PMC article.
NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization.
Su J, Wu G, Ye Y, Zhang J, Zeng L, Huang X, Zheng Y, Bai R, Zhuang L, Li M, Pan L, Deng J, Li R, Deng S, Zhang S, Zuo Z, Liu Z, Lin J, Lin D, Zheng J. Su J, et al. Among authors: zhang s, zhang j. Oncogene. 2021 Sep;40(39):5814-5828. doi: 10.1038/s41388-021-01978-0. Epub 2021 Aug 3. Oncogene. 2021. PMID: 34345012 Free PMC article.
N6 -methyladenosine-Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression.
Deng J, Zhang J, Ye Y, Liu K, Zeng L, Huang J, Pan L, Li M, Bai R, Zhuang L, Huang X, Wu G, Wei L, Zheng Y, Su J, Zhang S, Chen R, Lin D, Zheng J. Deng J, et al. Among authors: zhang s, zhang j. Cancer Res. 2021 Oct 15;81(20):5268-5283. doi: 10.1158/0008-5472.CAN-21-0494. Epub 2021 Aug 6. Cancer Res. 2021. PMID: 34362795 Free PMC article.
Inflammatory cytokine-regulated tRNA-derived fragment tRF-21 suppresses pancreatic ductal adenocarcinoma progression.
Pan L, Huang X, Liu ZX, Ye Y, Li R, Zhang J, Wu G, Bai R, Zhuang L, Wei L, Li M, Zheng Y, Su J, Deng J, Deng S, Zeng L, Zhang S, Wu C, Che X, Wang C, Chen R, Lin D, Zheng J. Pan L, et al. Among authors: zhang s, zhang j. J Clin Invest. 2021 Nov 15;131(22):e148130. doi: 10.1172/JCI148130. J Clin Invest. 2021. PMID: 34779408 Free PMC article.
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