Zhang SP - Search Results

1

Identification of potent phenyl imidazoles as opioid receptor agonists.

Breslin HJ, Cai C, Miskowski TA, Coutinho SV, Zhang SP, Hornby P, He W. Breslin HJ, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2006 May 1;16(9):2505-8. doi: 10.1016/j.bmcl.2006.01.082. Epub 2006 Feb 17. Bioorg Med Chem Lett. 2006. PMID: 16483774

2

Identification of a dual δ OR antagonist/μ OR agonist as a potential therapeutic for diarrhea-predominant Irritable Bowel Syndrome (IBS-d).

Breslin HJ, Diamond CJ, Kavash RW, Cai C, Dyatkin AB, Miskowski TA, Zhang SP, Wade PR, Hornby PJ, He W. Breslin HJ, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4869-72. doi: 10.1016/j.bmcl.2012.05.042. Epub 2012 May 24. Bioorg Med Chem Lett. 2012. PMID: 22695132

3

Rationale, design, and synthesis of novel phenyl imidazoles as opioid receptor agonists for gastrointestinal disorders.

Breslin HJ, Miskowski TA, Rafferty BM, Coutinho SV, Palmer JM, Wallace NH, Schneider CR, Kimball ES, Zhang SP, Li J, Colburn RW, Stone DJ, Martinez RP, He W. Breslin HJ, et al. Among authors: zhang sp. J Med Chem. 2004 Oct 7;47(21):5009-20. doi: 10.1021/jm030548r. J Med Chem. 2004. PMID: 15456245

4

Parallel methods for the preparation and SAR exploration of N-ethyl-4-[(8-alkyl-8-aza-bicyclo[3.2.1]oct-3-ylidene)-aryl-methyl]-benzamides, powerful mu and delta opioid agonists.

Coats SJ, Schulz MJ, Carson JR, Codd EE, Hlasta DJ, Pitis PM, Stone DJ Jr, Zhang SP, Colburn RW, Dax SL. Coats SJ, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5493-8. doi: 10.1016/j.bmcl.2004.09.004. Bioorg Med Chem Lett. 2004. PMID: 15482911

5

N,N-dialkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, potent, selective delta opioid agonists.

Carson JR, Coats SJ, Codd EE, Dax SL, Lee J, Martinez RP, Neilson LA, Pitis PM, Zhang SP. Carson JR, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2004 May 3;14(9):2109-12. doi: 10.1016/j.bmcl.2004.02.051. Bioorg Med Chem Lett. 2004. PMID: 15080989

6

N-alkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, micro and delta opioid agonists: a micro address.

Carson JR, Coats SJ, Codd EE, Dax SL, Lee J, Martinez RP, McKown LA, Anne Neilson L, Pitis PM, Wu WN, Zhang SP. Carson JR, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2004 May 3;14(9):2113-6. doi: 10.1016/j.bmcl.2004.02.052. Bioorg Med Chem Lett. 2004. PMID: 15080990

7

Synthesis and binding affinities of 4-diarylaminotropanes, a new class of delta opioid agonists.

Boyd RE, Carson JR, Codd EE, Gauthier AD, Neilson LA, Zhang SP. Boyd RE, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2000 May 15;10(10):1109-11. doi: 10.1016/s0960-894x(00)00182-7. Bioorg Med Chem Lett. 2000. PMID: 10843229

8

Ex vivo delta opioid receptor autoradiography: CNS receptor occupancy of two novel compounds over their antihyperalgesic dose range.

Codd EE, Ma J, Zhang SP, Stone DJ Jr, Colburn RW, Brandt MR, Chevalier KM, Zhu Y, Peng S, Cai C, Acton PD, Flores CM. Codd EE, et al. Among authors: zhang sp. Pharmacol Biochem Behav. 2010 Aug;96(2):130-5. doi: 10.1016/j.pbb.2010.04.020. Epub 2010 May 12. Pharmacol Biochem Behav. 2010. PMID: 20438745

9

Piperazinyl benzamidines: synthesis and affinity for the delta opioid receptor.

Nortey SO, Baxter EW, Codd EE, Zhang SP, Reitz AB. Nortey SO, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2001 Jul 9;11(13):1741-3. doi: 10.1016/s0960-894x(01)00272-4. Bioorg Med Chem Lett. 2001. PMID: 11425550

10

Heteroaryl beta-tetralin ureas as novel antagonists of human TRPV1.

Jetter MC, Youngman MA, McNally JJ, McDonnell ME, Zhang SP, Dubin AE, Nasser N, Codd EE, Flores CM, Dax SL. Jetter MC, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6160-3. doi: 10.1016/j.bmcl.2007.09.036. Epub 2007 Sep 12. Bioorg Med Chem Lett. 2007. PMID: 17892935

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