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Significance of heat-stable and heat-labile enterotoxins in porcine colibacillosis in an additive model for pathogenicity studies.
Zhang W, Berberov EM, Freeling J, He D, Moxley RA, Francis DH. Zhang W, et al. Infect Immun. 2006 Jun;74(6):3107-14. doi: 10.1128/IAI.01338-05. Infect Immun. 2006. PMID: 16714538 Free PMC article.
Escherichia coli constructs expressing human or porcine enterotoxins induce identical diarrheal diseases in a piglet infection model.
Zhang W, Robertson DC, Zhang C, Bai W, Zhao M, Francis DH. Zhang W, et al. Appl Environ Microbiol. 2008 Sep;74(18):5832-7. doi: 10.1128/AEM.00893-08. Epub 2008 Jul 25. Appl Environ Microbiol. 2008. PMID: 18658289 Free PMC article.
Characterization of the binding specificity of K88ac and K88ad fimbriae of enterotoxigenic Escherichia coli by constructing K88ac/K88ad chimeric FaeG major subunits.
Zhang W, Fang Y, Francis DH. Zhang W, et al. Infect Immun. 2009 Feb;77(2):699-706. doi: 10.1128/IAI.01165-08. Epub 2008 Nov 17. Infect Immun. 2009. PMID: 19015246 Free PMC article.
Little heterogeneity among genes encoding heat-labile and heat-stable toxins of enterotoxigenic Escherichia coli strains isolated from diarrheal pigs.
Zhang C, Rausch D, Zhang W. Zhang C, et al. Appl Environ Microbiol. 2009 Oct;75(19):6402-5. doi: 10.1128/AEM.00952-09. Epub 2009 Aug 14. Appl Environ Microbiol. 2009. PMID: 19684170 Free PMC article.
Genetic fusions of heat-labile (LT) and heat-stable (ST) toxoids of porcine enterotoxigenic Escherichia coli elicit neutralizing anti-LT and anti-STa antibodies.
Zhang W, Zhang C, Francis DH, Fang Y, Knudsen D, Nataro JP, Robertson DC. Zhang W, et al. Infect Immun. 2010 Jan;78(1):316-25. doi: 10.1128/IAI.00497-09. Epub 2009 Oct 26. Infect Immun. 2010. PMID: 19858307 Free PMC article.
Genetic fusions of heat-labile toxoid (LT) and heat-stable toxin b (STb) of porcine enterotoxigenic Escherichia coli elicit protective anti-LT and anti-STb antibodies.
Zhang W, Francis DH. Zhang W, et al. Clin Vaccine Immunol. 2010 Aug;17(8):1223-31. doi: 10.1128/CVI.00095-10. Epub 2010 May 26. Clin Vaccine Immunol. 2010. PMID: 20505006 Free PMC article.
Escherichia coli K88ac fimbriae expressing heat-labile and heat-stable (STa) toxin epitopes elicit antibodies that neutralize cholera toxin and STa toxin and inhibit adherence of K88ac fimbrial E. coli.
Zhang C, Zhang W. Zhang C, et al. Clin Vaccine Immunol. 2010 Dec;17(12):1859-67. doi: 10.1128/CVI.00251-10. Epub 2010 Oct 27. Clin Vaccine Immunol. 2010. PMID: 20980482 Free PMC article.
Heat-labile- and heat-stable-toxoid fusions (LTR₁₉₂G-STaP₁₃F) of human enterotoxigenic Escherichia coli elicit neutralizing antitoxin antibodies.
Liu M, Ruan X, Zhang C, Lawson SR, Knudsen DE, Nataro JP, Robertson DC, Zhang W. Liu M, et al. Infect Immun. 2011 Oct;79(10):4002-9. doi: 10.1128/IAI.00165-11. Epub 2011 Jul 25. Infect Immun. 2011. PMID: 21788385 Free PMC article.
Our recent study showed that porcine-type STa toxoids became immunogenic and elicited neutralizing anti-STa antibodies after being genetically fused to a full-length porcine-type LT toxoid, LT(R₁₉₂G) (W. Zhang et al., Infect. Immun. 78:316-325, 2010). In this study, …
Our recent study showed that porcine-type STa toxoids became immunogenic and elicited neutralizing anti-STa antibodies after being genetical …
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