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SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex.
Cao R, Zhang Y. Cao R, et al. Among authors: zhang y. Mol Cell. 2004 Jul 2;15(1):57-67. doi: 10.1016/j.molcel.2004.06.020. Mol Cell. 2004. PMID: 15225548
AOF1 is a histone H3K4 demethylase possessing demethylase activity-independent repression function.
Yang Z, Jiang J, Stewart MD, Qi S, Yamane K, Li J, Zhang Y, Wong J. Yang Z, et al. Among authors: zhang y. Cell Res. 2010 Mar;20(3):276-87. doi: 10.1038/cr.2010.12. Epub 2010 Jan 26. Cell Res. 2010. PMID: 20101264 Free PMC article.
Purification of histone demethylases from HeLa cells.
Tsukada Y, Zhang Y. Tsukada Y, et al. Among authors: zhang y. Methods. 2006 Dec;40(4):318-26. doi: 10.1016/j.ymeth.2006.06.024. Methods. 2006. PMID: 17101443 Free PMC article.
MES-4: an autosome-associated histone methyltransferase that participates in silencing the X chromosomes in the C. elegans germ line.
Bender LB, Suh J, Carroll CR, Fong Y, Fingerman IM, Briggs SD, Cao R, Zhang Y, Reinke V, Strome S. Bender LB, et al. Among authors: zhang y. Development. 2006 Oct;133(19):3907-17. doi: 10.1242/dev.02584. Development. 2006. PMID: 16968818 Free PMC article.
pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.
Kotake Y, Cao R, Viatour P, Sage J, Zhang Y, Xiong Y. Kotake Y, et al. Among authors: zhang y. Genes Dev. 2007 Jan 1;21(1):49-54. doi: 10.1101/gad.1499407. Genes Dev. 2007. PMID: 17210787 Free PMC article.
DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
Nguyen AT, Taranova O, He J, Zhang Y. Nguyen AT, et al. Among authors: zhang y. Blood. 2011 Jun 23;117(25):6912-22. doi: 10.1182/blood-2011-02-334359. Epub 2011 Apr 26. Blood. 2011. PMID: 21521783 Free PMC article.
JmjC-domain-containing proteins and histone demethylation.
Klose RJ, Kallin EM, Zhang Y. Klose RJ, et al. Among authors: zhang y. Nat Rev Genet. 2006 Sep;7(9):715-27. doi: 10.1038/nrg1945. Nat Rev Genet. 2006. PMID: 16983801
Histone demethylation by a family of JmjC domain-containing proteins.
Tsukada Y, Fang J, Erdjument-Bromage H, Warren ME, Borchers CH, Tempst P, Zhang Y. Tsukada Y, et al. Among authors: zhang y. Nature. 2006 Feb 16;439(7078):811-6. doi: 10.1038/nature04433. Epub 2005 Dec 18. Nature. 2006. PMID: 16362057
Role of histone H2A ubiquitination in Polycomb silencing.
Wang H, Wang L, Erdjument-Bromage H, Vidal M, Tempst P, Jones RS, Zhang Y. Wang H, et al. Among authors: zhang y. Nature. 2004 Oct 14;431(7010):873-8. doi: 10.1038/nature02985. Epub 2004 Sep 22. Nature. 2004. PMID: 15386022
The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3.
Cao R, Zhang Y. Cao R, et al. Among authors: zhang y. Curr Opin Genet Dev. 2004 Apr;14(2):155-64. doi: 10.1016/j.gde.2004.02.001. Curr Opin Genet Dev. 2004. PMID: 15196462 Review.
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