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140,926 results
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RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling.
Zhang Y, Liu S, Mickanin C, Feng Y, Charlat O, Michaud GA, Schirle M, Shi X, Hild M, Bauer A, Myer VE, Finan PM, Porter JA, Huang SM, Cong F. Zhang Y, et al. Nat Cell Biol. 2011 May;13(5):623-9. doi: 10.1038/ncb2222. Epub 2011 Apr 10. Nat Cell Biol. 2011. PMID: 21478859
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.
Ruffner H, Sprunger J, Charlat O, Leighton-Davies J, Grosshans B, Salathe A, Zietzling S, Beck V, Therier M, Isken A, Xie Y, Zhang Y, Hao H, Shi X, Liu D, Song Q, Clay I, Hintzen G, Tchorz J, Bouchez LC, Michaud G, Finan P, Myer VE, Bouwmeester T, Porter J, Hild M, Bassilana F, Parker CN, Cong F. Ruffner H, et al. Among authors: zhang y. PLoS One. 2012;7(7):e40976. doi: 10.1371/journal.pone.0040976. Epub 2012 Jul 16. PLoS One. 2012. PMID: 22815884 Free PMC article.
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.
Hao HX, Xie Y, Zhang Y, Charlat O, Oster E, Avello M, Lei H, Mickanin C, Liu D, Ruffner H, Mao X, Ma Q, Zamponi R, Bouwmeester T, Finan PM, Kirschner MW, Porter JA, Serluca FC, Cong F. Hao HX, et al. Among authors: zhang y. Nature. 2012 Apr 29;485(7397):195-200. doi: 10.1038/nature11019. Nature. 2012. PMID: 22575959
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.
Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F. Huang SM, et al. Among authors: zhang y. Nature. 2009 Oct 1;461(7264):614-20. doi: 10.1038/nature08356. Epub 2009 Sep 16. Nature. 2009. PMID: 19759537
Pyrimidinone nicotinamide mimetics as selective tankyrase and wnt pathway inhibitors suitable for in vivo pharmacology.
Johannes JW, Almeida L, Barlaam B, Boriack-Sjodin PA, Casella R, Croft RA, Dishington AP, Gingipalli L, Gu C, Hawkins JL, Holmes JL, Howard T, Huang J, Ioannidis S, Kazmirski S, Lamb ML, McGuire TM, Moore JE, Ogg D, Patel A, Pike KG, Pontz T, Robb GR, Su N, Wang H, Wu X, Zhang HJ, Zhang Y, Zheng X, Wang T. Johannes JW, et al. Among authors: zhang hj, zhang y. ACS Med Chem Lett. 2015 Jan 13;6(3):254-9. doi: 10.1021/ml5003663. eCollection 2015 Mar 12. ACS Med Chem Lett. 2015. PMID: 25815142 Free PMC article.
Interferon-γ decreases ATP-binding cassette subfamily G member 1 (ABCG1)-mediated cholesterol efflux through small ubiquitin-like modifier (SUMO)/ubiquitin-dependent liver X receptor-α degradation in macrophages.
Dong M, Zhang Y, Xu C, Wang C, Liu M, Zhang Z, Wu H, Yuan Z, Zhou J. Dong M, et al. Among authors: zhang y. Biotechnol Appl Biochem. 2020 Oct 30. doi: 10.1002/bab.2063. Online ahead of print. Biotechnol Appl Biochem. 2020. PMID: 33125792
Detection and structural characterization of the metabolites of dihydroresveratrol in rats by liquid chromatography coupled to high resolution tandem mass spectrometry.
Ji QG, Ma MH, Hu XM, Zhang YJ, Xu XH, Nian H. Ji QG, et al. Among authors: zhang yj. Rapid Commun Mass Spectrom. 2020 Oct 30:e8991. doi: 10.1002/rcm.8991. Online ahead of print. Rapid Commun Mass Spectrom. 2020. PMID: 33125777
Unfractionated heparin inhibits live wild-type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations.
Tree JA, Turnbull JE, Buttigieg KR, Elmore MJ, Coombes N, Hogwood J, Mycroft-West CJ, Lima MA, Skidmore MA, Karlsson R, Chen YH, Zhang Y, Spalluto CM, Staples KJ, Yates EA, Gray E, Singh D, Wilkinson T, Page CP, Carroll MW. Tree JA, et al. Among authors: zhang y. Br J Pharmacol. 2020 Oct 30. doi: 10.1111/bph.15304. Online ahead of print. Br J Pharmacol. 2020. PMID: 33125711
Twin sisters with Hashimoto's thyroiditis and Henoch-Schönlein purpura.
Wang XL, Wang YX, Liu M, Cheng Y, He XJ, Zhang YL. Wang XL, et al. Among authors: zhang yl. Endokrynol Pol. 2020 Oct 30. doi: 10.5603/EP.a2020.0069. Online ahead of print. Endokrynol Pol. 2020. PMID: 33125698
Senescence-associated β-galactosidase in subcutaneous adipose tissue associates with altered glycaemic status and truncal fat in severe obesity.
Rouault C, Marcelin G, Adriouch S, Rose C, Genser L, Ambrosini M, Bichet JC, Zhang Y, Marquet F, Aron-Wisnewsky J, Poitou C, André S, Dérumeaux G, Guerre-Millo M, Clément K. Rouault C, et al. Among authors: zhang y. Diabetologia. 2020 Oct 30. doi: 10.1007/s00125-020-05307-0. Online ahead of print. Diabetologia. 2020. PMID: 33125520
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