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Mesenchymal stem cells deliver and release conditionally replicative adenovirus depending on hepatic differentiation to eliminate hepatocellular carcinoma cells specifically.
Yuan X, Zhang Q, Li Z, Zhang X, Bao S, Fan D, Ru Y, Dong S, Zhang Y, Zhang Y, Ye Z, Xiong D. Yuan X, et al. Among authors: Zhang Q, Zhang X, Zhang Y, Zhang Y. Cancer Lett. 2016 Oct 10;381(1):85-95. doi: 10.1016/j.canlet.2016.07.019. Epub 2016 Jul 20. Cancer Lett. 2016. PMID: 27450327
Bispecific CD3-HAC carried by E1A-engineered mesenchymal stromal cells against metastatic breast cancer by blocking PD-L1 and activating T cells.
Yang Y, Zhang X, Lin F, Xiong M, Fan D, Yuan X, Lu Y, Song Y, Zhang Y, Hao M, Ye Z, Zhang Y, Wang J, Xiong D. Yang Y, et al. Among authors: Zhang X, Zhang Y, Zhang Y. J Hematol Oncol. 2019 Apr 25;12(1):46. doi: 10.1186/s13045-019-0723-8. J Hematol Oncol. 2019. PMID: 31023384 Free PMC article.
Mesenchymal stromal cells as vehicles of tetravalent bispecific Tandab (CD3/CD19) for the treatment of B cell lymphoma combined with IDO pathway inhibitor D-1-methyl-tryptophan.
Zhang X, Yang Y, Zhang L, Lu Y, Zhang Q, Fan D, Zhang Y, Zhang Y, Ye Z, Xiong D. Zhang X, et al. Among authors: Zhang L, Zhang Q, Zhang Y, Zhang Y. J Hematol Oncol. 2017 Feb 23;10(1):56. doi: 10.1186/s13045-017-0397-z. J Hematol Oncol. 2017. PMID: 28228105 Free PMC article.
C/EBPα negatively regulates SIRT7 expression via recruiting HDAC3 to the upstream-promoter of hepatocellular carcinoma cells.
Liu GF, Lu JY, Zhang YJ, Zhang LX, Lu GD, Xie ZJ, Cheng MB, Shen YF, Zhang Y. Liu GF, et al. Among authors: Zhang YJ, Zhang LX, Zhang Y. Biochim Biophys Acta. 2016 Feb;1859(2):348-54. doi: 10.1016/j.bbagrm.2015.12.004. Epub 2015 Dec 15. Biochim Biophys Acta. 2016. PMID: 26704017
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