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Chemoprotection against cancer by phase 2 enzyme induction.
Talalay P, Fahey JW, Holtzclaw WD, Prestera T, Zhang Y. Talalay P, et al. Among authors: zhang y. Toxicol Lett. 1995 Dec;82-83:173-9. doi: 10.1016/0378-4274(95)03553-2. Toxicol Lett. 1995. PMID: 8597048 Free article. Review.
Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes.
Posner GH, Cho CG, Green JV, Zhang Y, Talalay P. Posner GH, et al. Among authors: zhang y. J Med Chem. 1994 Jan 7;37(1):170-6. doi: 10.1021/jm00027a021. J Med Chem. 1994. PMID: 8289191
Thirty-five bifunctional isothiocyanates were synthesized as structural analogs of sulforaphane [(-)-1-isothiocyanato-4(R)-(methylsulfinyl)butane] that was recently isolated from broccoli as the principal and very potent inducer of detoxication (phase 2) enzymes in mouse tissues …
Thirty-five bifunctional isothiocyanates were synthesized as structural analogs of sulforaphane [(-)-1-isothiocyanato-4(R)-(methylsulfinyl)b …
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