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6,252 results
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ATP citrate lyase is an important component of cell growth and transformation.
Bauer DE, Hatzivassiliou G, Zhao F, Andreadis C, Thompson CB. Bauer DE, et al. Oncogene. 2005 Sep 15;24(41):6314-22. doi: 10.1038/sj.onc.1208773. Oncogene. 2005. PMID: 16007201
The molecular determinants of de novo nucleotide biosynthesis in cancer cells.
Tong X, Zhao F, Thompson CB. Tong X, et al. Curr Opin Genet Dev. 2009 Feb;19(1):32-7. doi: 10.1016/j.gde.2009.01.002. Epub 2009 Feb 5. Curr Opin Genet Dev. 2009. PMID: 19201187 Free PMC article. Review.
The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation.
Tong X, Zhao F, Mancuso A, Gruber JJ, Thompson CB. Tong X, et al. Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21660-5. doi: 10.1073/pnas.0911316106. Epub 2009 Dec 7. Proc Natl Acad Sci U S A. 2009. PMID: 19995986 Free PMC article.
ATP citrate lyase inhibition can suppress tumor cell growth.
Hatzivassiliou G, Zhao F, Bauer DE, Andreadis C, Shaw AN, Dhanak D, Hingorani SR, Tuveson DA, Thompson CB. Hatzivassiliou G, et al. Cancer Cell. 2005 Oct;8(4):311-21. doi: 10.1016/j.ccr.2005.09.008. Cancer Cell. 2005. PMID: 16226706
Many tumors display a high rate of glucose utilization, as evidenced by 18-F-2-deoxyglucose PET imaging. One potential advantage of catabolizing glucose through glycolysis at a rate that exceeds bioenergetic need is that the growing cell can redirect the excess glycolytic …
Many tumors display a high rate of glucose utilization, as evidenced by 18-F-2-deoxyglucose PET imaging. One potential advantage of c …
How do cancer cells acquire the fuel needed to support cell growth?
Thompson CB, Bauer DE, Lum JJ, Hatzivassiliou G, Zong WX, Zhao F, Ditsworth D, Buzzai M, Lindsten T. Thompson CB, et al. Cold Spring Harb Symp Quant Biol. 2005;70:357-62. doi: 10.1101/sqb.2005.70.011. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869772
Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming.
Zhao F, Mancuso A, Bui TV, Tong X, Gruber JJ, Swider CR, Sanchez PV, Lum JJ, Sayed N, Melo JV, Perl AE, Carroll M, Tuttle SW, Thompson CB. Zhao F, et al. Oncogene. 2010 May 20;29(20):2962-72. doi: 10.1038/onc.2010.67. Epub 2010 Mar 15. Oncogene. 2010. PMID: 20228846 Free PMC article.
Promotion of cell cycle progression by basic helix-loop-helix E2A.
Zhao F, Vilardi A, Neely RJ, Choi JK. Zhao F, et al. Mol Cell Biol. 2001 Sep;21(18):6346-57. doi: 10.1128/mcb.21.18.6346-6357.2001. Mol Cell Biol. 2001. PMID: 11509675 Free PMC article.
The involvement of Ran GTPase in lipopolysaccharide endotoxin-induced responses.
Zhao F, Yuan Q, Sultzer BM, Chung SW, Wong PM. Zhao F, et al. J Endotoxin Res. 2001;7(1):53-6. doi: 10.1179/096805101101532549. J Endotoxin Res. 2001. PMID: 11521083
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation.
Kundu M, Lindsten T, Yang CY, Wu J, Zhao F, Zhang J, Selak MA, Ney PA, Thompson CB. Kundu M, et al. Blood. 2008 Aug 15;112(4):1493-502. doi: 10.1182/blood-2008-02-137398. Epub 2008 Jun 6. Blood. 2008. PMID: 18539900 Free PMC article.
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