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The phosphatidylinositol 3-kinases (PI3K) inhibitor GS-1101 synergistically potentiates histone deacetylase inhibitor-induced proliferation inhibition and apoptosis through the inactivation of PI3K and extracellular signal-regulated kinase pathways.
Bodo J, Zhao X, Sharma A, Hill BT, Portell CA, Lannutti BJ, Almasan A, Hsi ED. Bodo J, et al. Among authors: zhao x. Br J Haematol. 2013 Oct;163(1):72-80. doi: 10.1111/bjh.12498. Epub 2013 Jul 25. Br J Haematol. 2013. PMID: 23889282 Free PMC article.
CCMCL1: a new model of aggressive mantle cell lymphoma.
Zhao X, Chen-Kiang S, Shetty S, Di Liberto M, Bodo J, Durkin L, Eng K, Elemento O, Smith MR, Hsi ED. Zhao X, et al. Blood. 2015 Apr 23;125(17):2730-2. doi: 10.1182/blood-2015-01-622795. Blood. 2015. PMID: 25907904 Free PMC article. No abstract available.
A novel CDK9 inhibitor increases the efficacy of venetoclax (ABT-199) in multiple models of hematologic malignancies.
Phillips DC, Jin S, Gregory GP, Zhang Q, Xue J, Zhao X, Chen J, Tong Y, Zhang H, Smith M, Tahir SK, Clark RF, Penning TD, Devlin JR, Shortt J, Hsi ED, Albert DH, Konopleva M, Johnstone RW, Leverson JD, Souers AJ. Phillips DC, et al. Among authors: zhao x. Leukemia. 2020 Jun;34(6):1646-1657. doi: 10.1038/s41375-019-0652-0. Epub 2019 Dec 11. Leukemia. 2020. PMID: 31827241 Free PMC article.
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