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FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.
Zhao X, Yang Y, Sun BF, Shi Y, Yang X, Xiao W, Hao YJ, Ping XL, Chen YS, Wang WJ, Jin KX, Wang X, Huang CM, Fu Y, Ge XM, Song SH, Jeong HS, Yanagisawa H, Niu Y, Jia GF, Wu W, Tong WM, Okamoto A, He C, Rendtlew Danielsen JM, Wang XJ, Yang YG. Zhao X, et al. Cell Res. 2014 Dec;24(12):1403-19. doi: 10.1038/cr.2014.151. Epub 2014 Nov 21. Cell Res. 2014. PMID: 25412662 Free PMC article.
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.
Zheng G, Dahl JA, Niu Y, Fedorcsak P, Huang CM, Li CJ, Vågbø CB, Shi Y, Wang WL, Song SH, Lu Z, Bosmans RP, Dai Q, Hao YJ, Yang X, Zhao WM, Tong WM, Wang XJ, Bogdan F, Furu K, Fu Y, Jia G, Zhao X, Liu J, Krokan HE, Klungland A, Yang YG, He C. Zheng G, et al. Among authors: zhao wm, zhao x. Mol Cell. 2013 Jan 10;49(1):18-29. doi: 10.1016/j.molcel.2012.10.015. Epub 2012 Nov 21. Mol Cell. 2013. PMID: 23177736 Free PMC article.
FTO and obesity: mechanisms of association.
Zhao X, Yang Y, Sun BF, Zhao YL, Yang YG. Zhao X, et al. Among authors: zhao yl. Curr Diab Rep. 2014;14(5):486. doi: 10.1007/s11892-014-0486-0. Curr Diab Rep. 2014. PMID: 24627050 Review.
Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase.
Ping XL, Sun BF, Wang L, Xiao W, Yang X, Wang WJ, Adhikari S, Shi Y, Lv Y, Chen YS, Zhao X, Li A, Yang Y, Dahal U, Lou XM, Liu X, Huang J, Yuan WP, Zhu XF, Cheng T, Zhao YL, Wang X, Rendtlew Danielsen JM, Liu F, Yang YG. Ping XL, et al. Among authors: zhao x, zhao yl. Cell Res. 2014 Feb;24(2):177-89. doi: 10.1038/cr.2014.3. Epub 2014 Jan 10. Cell Res. 2014. PMID: 24407421 Free PMC article.
m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency.
Chen T, Hao YJ, Zhang Y, Li MM, Wang M, Han W, Wu Y, Lv Y, Hao J, Wang L, Li A, Yang Y, Jin KX, Zhao X, Li Y, Ping XL, Lai WY, Wu LG, Jiang G, Wang HL, Sang L, Wang XJ, Yang YG, Zhou Q. Chen T, et al. Among authors: zhao x. Cell Stem Cell. 2015 Mar 5;16(3):289-301. doi: 10.1016/j.stem.2015.01.016. Epub 2015 Feb 12. Cell Stem Cell. 2015. PMID: 25683224 Free article.
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