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IL-6 trans-signaling promotes the expansion and anti-tumor activity of CAR T cells.
Jiang Z, Liao R, Lv J, Li S, Zheng D, Qin L, Wu D, Chen S, Long Y, Wu Q, Wang S, Lin S, Huang X, Tang Z, Shi P, Zhou H, Liu Q, Zhao R, Li Y, Jie Y, Wei W, Lai P, Du X, Cui S, Weinkove R, Liu P, Pei D, Yao Y, Li P. Jiang Z, et al. Among authors: zheng d. Leukemia. 2021 May;35(5):1380-1391. doi: 10.1038/s41375-020-01085-1. Epub 2020 Nov 9. Leukemia. 2021. PMID: 33168950
Mesothelin is a target of chimeric antigen receptor T cells for treating gastric cancer.
Lv J, Zhao R, Wu D, Zheng D, Wu Z, Shi J, Wei X, Wu Q, Long Y, Lin S, Wang S, Wang Z, Li Y, Chen Y, He Q, Chen S, Yao H, Liu Z, Tang Z, Yao Y, Pei D, Liu P, Zhang X, Zhang Z, Cui S, Chen R, Li P. Lv J, et al. Among authors: zheng d. J Hematol Oncol. 2019 Feb 18;12(1):18. doi: 10.1186/s13045-019-0704-y. J Hematol Oncol. 2019. PMID: 30777106 Free PMC article.
Myeloid-derived suppressor cells promote lung cancer metastasis by CCL11 to activate ERK and AKT signaling and induce epithelial-mesenchymal transition in tumor cells.
Lin S, Zhang X, Huang G, Cheng L, Lv J, Zheng D, Lin S, Wang S, Wu Q, Long Y, Li B, Wei W, Liu P, Pei D, Li Y, Wen Z, Cui S, Li P, Sun X, Wu Y, Yao Y. Lin S, et al. Among authors: zheng d. Oncogene. 2021 Feb;40(8):1476-1489. doi: 10.1038/s41388-020-01605-4. Epub 2021 Jan 15. Oncogene. 2021. PMID: 33452453
Human induced-T-to-natural killer cells have potent anti-tumour activities.
Jiang Z, Qin L, Tang Y, Liao R, Shi J, He B, Li S, Zheng D, Cui Y, Wu Q, Long Y, Yao Y, Wei Z, Hong Q, Wu Y, Mai Y, Gou S, Li X, Weinkove R, Norton S, Luo W, Feng W, Zhou H, Liu Q, Chen J, Lai L, Chen X, Pei D, Graf T, Liu X, Li Y, Liu P, Zhang Z, Li P. Jiang Z, et al. Among authors: zheng d. Biomark Res. 2022 Mar 24;10(1):13. doi: 10.1186/s40364-022-00358-4. Biomark Res. 2022. PMID: 35331335 Free PMC article.
DAP10 integration in CAR-T cells enhances the killing of heterogeneous tumors by harnessing endogenous NKG2D.
Li S, Zhao R, Zheng D, Qin L, Cui Y, Li Y, Jiang Z, Zhong M, Shi J, Li M, Wang X, Tang Z, Wu Q, Long Y, Hu D, Wang S, Yao Y, Liu S, Yang LH, Zhang Z, Tang Q, Liu P, Li Y, Li P. Li S, et al. Among authors: zheng d. Mol Ther Oncolytics. 2022 Jun 6;26:15-26. doi: 10.1016/j.omto.2022.06.003. eCollection 2022 Sep 15. Mol Ther Oncolytics. 2022. PMID: 35784403 Free PMC article.
5,457 results