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Vagus nerve stimulation activates two distinct neuroimmune circuits converging in the spleen to protect mice from kidney injury.
Tanaka S, Abe C, Abbott SBG, Zheng S, Yamaoka Y, Lipsey JE, Skrypnyk NI, Yao J, Inoue T, Nash WT, Stornetta DS, Rosin DL, Stornetta RL, Guyenet PG, Okusa MD. Tanaka S, et al. Among authors: zheng s. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2021758118. doi: 10.1073/pnas.2021758118. Proc Natl Acad Sci U S A. 2021. PMID: 33737395 Free PMC article.
Non-canonical cholinergic anti-inflammatory pathway-mediated activation of peritoneal macrophages induces Hes1 and blocks ischemia/reperfusion injury in the kidney.
Inoue T, Abe C, Kohro T, Tanaka S, Huang L, Yao J, Zheng S, Ye H, Inagi R, Stornetta RL, Rosin DL, Nangaku M, Wada Y, Okusa MD. Inoue T, et al. Among authors: zheng s. Kidney Int. 2019 Mar;95(3):563-576. doi: 10.1016/j.kint.2018.09.020. Epub 2019 Jan 19. Kidney Int. 2019. PMID: 30670317 Free PMC article.
Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney.
Tanaka S, Zheng S, Kharel Y, Fritzemeier RG, Huang T, Foster D, Poudel N, Goggins E, Yamaoka Y, Rudnicka KP, Lipsey JE, Radel HV, Ryuh SM, Inoue T, Yao J, Rosin DL, Schwab SR, Santos WL, Lynch KR, Okusa MD. Tanaka S, et al. Among authors: zheng s. Sci Transl Med. 2022 Aug 17;14(658):eabj2681. doi: 10.1126/scitranslmed.abj2681. Epub 2022 Aug 17. Sci Transl Med. 2022. PMID: 35976996 Free PMC article.
Human Recombinant Alkaline Phosphatase (Ilofotase Alfa) Protects Against Kidney Ischemia-Reperfusion Injury in Mice and Rats Through Adenosine Receptors.
Rosin DL, Hall JP, Zheng S, Huang L, Campos-Bilderback S, Sandoval R, Bree A, Beaumont K, Miller E, Larsen J, Hariri G, Kaila N, Encarnacion IM, Gale JD, van Elsas A, Molitoris BA, Okusa MD. Rosin DL, et al. Among authors: zheng s. Front Med (Lausanne). 2022 Jul 28;9:931293. doi: 10.3389/fmed.2022.931293. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35966871 Free PMC article.
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