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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 2
2004 3
2005 1
2006 5
2007 2
2008 8
2009 7
2010 13
2011 11
2012 17
2013 18
2014 12
2015 11
2016 7
2017 14
2018 22
2019 31
2020 31
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198 results
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LncRNA PICSAR promotes cell proliferation, migration and invasion of fibroblast-like synoviocytes by sponging miRNA-4701-5p in rheumatoid arthritis.
Bi X, Guo XH, Mo BY, Wang ML, Luo XQ, Chen YX, Liu F, Olsen N, Pan YF, Zheng SG. Bi X, et al. EBioMedicine. 2019 Dec;50:408-420. doi: 10.1016/j.ebiom.2019.11.024. Epub 2019 Nov 30. EBioMedicine. 2019. PMID: 31791845 Free PMC article.
Fibroblast-like synoviocytes (FLSs), a prominent component of hyperplastic synovial pannus tissue, are the primary effector cells in RA synovial hyperplasia and invasion which can lead to joint destruction. ...The cell proliferation, migration, invasion and proinfla …
Fibroblast-like synoviocytes (FLSs), a prominent component of hyperplastic synovial pannus tissue, are the primary effector cells in …
Pik3ip1 Is a Negative Immune Regulator that Inhibits Antitumor T-Cell Immunity.
Chen Y, Wang J, Wang X, Li X, Song J, Fang J, Liu X, Liu T, Wang D, Li Q, Wen S, Ma D, Xia J, Luo L, Zheng SG, Cui J, Zeng G, Chen L, Cheng B, Wang Z. Chen Y, et al. Clin Cancer Res. 2019 Oct 15;25(20):6180-6194. doi: 10.1158/1078-0432.CCR-18-4134. Epub 2019 Jul 26. Clin Cancer Res. 2019. PMID: 31350312 Free article.
PURPOSE: Multiple negative regulators restrict the ability of T cells to attack tumors. This work demonstrates the role of PI3K-interacting protein 1 (Pik3ip1) in restraining T-cell responses and antitumor immunity. ...Pik3ip1 expression was quantified, and its impa …
PURPOSE: Multiple negative regulators restrict the ability of T cells to attack tumors. This work demonstrates the role of PI3K-inter …
Beyond Type 1 Regulatory T Cells: Co-expression of LAG3 and CD49b in IL-10-Producing T Cell Lineages.
Huang W, Solouki S, Carter C, Zheng SG, August A. Huang W, et al. Front Immunol. 2018 Nov 19;9:2625. doi: 10.3389/fimmu.2018.02625. eCollection 2018. Front Immunol. 2018. PMID: 30510554 Free PMC article.
Here, using an IL-10(GFP)/Foxp3(RFP) dual reporter transgenic murine model, we demonstrate that co-expression of CD49b and LAG3 is not restricted to the Foxp3(-) Tr1 cells, but is also observed in Foxp3(+) T regulatory (Treg) cells and CD8(+) T cells that pro …
Here, using an IL-10(GFP)/Foxp3(RFP) dual reporter transgenic murine model, we demonstrate that co-expression of CD49b and LAG3 is not restr …
Sonic Hedgehog Signaling Pathway Mediates Proliferation and Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via MAPK/ERK Signaling Pathway.
Liu F, Feng XX, Zhu SL, Huang HY, Chen YD, Pan YF, June RR, Zheng SG, Huang JL. Liu F, et al. Front Immunol. 2018 Dec 5;9:2847. doi: 10.3389/fimmu.2018.02847. eCollection 2018. Front Immunol. 2018. PMID: 30568656 Free PMC article.
Cell viability was detected using cell proliferation and cytotoxicity kit-8 (CCK8), and cell cycle distribution and proliferating cells were evaluated by the flow cytometry. ...RA-FLSs treated with Purmorphamine resulted in alteration of cell cy
Cell viability was detected using cell proliferation and cytotoxicity kit-8 (CCK8), and cell cycle distribution and pro
ILC2 frequency and activity are inhibited by glucocorticoid treatment via STAT pathway in patients with asthma.
Yu QN, Guo YB, Li X, Li CL, Tan WP, Fan XL, Qin ZL, Chen D, Wen WP, Zheng SG, Fu QL. Yu QN, et al. Allergy. 2018 Sep;73(9):1860-1870. doi: 10.1111/all.13438. Allergy. 2018. PMID: 29542140 Free PMC article.
BACKGROUND: Group 2 innate lymphoid cells (ILC2s) were closely associated with asthma. However, there were no perspective studies about the effects of glucocorticoid on ILC2s in asthma patients. ...
BACKGROUND: Group 2 innate lymphoid cells (ILC2s) were closely associated with asthma. However, there were no perspective studies abo …
Long noncoding RNA LERFS negatively regulates rheumatoid synovial aggression and proliferation.
Zou Y, Xu S, Xiao Y, Qiu Q, Shi M, Wang J, Liang L, Zhan Z, Yang X, Olsen N, Zheng SG, Xu H. Zou Y, et al. J Clin Invest. 2018 Oct 1;128(10):4510-4524. doi: 10.1172/JCI97965. Epub 2018 Sep 10. J Clin Invest. 2018. PMID: 30198906 Free PMC article. Clinical Trial.
Role of TNF-TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications.
Yang S, Wang J, Brand DD, Zheng SG. Yang S, et al. Front Immunol. 2018 Apr 19;9:784. doi: 10.3389/fimmu.2018.00784. eCollection 2018. Front Immunol. 2018. PMID: 29725328 Free PMC article. Review.
Emerging evidence has demonstrated that TNFR1 is ubiquitously expressed on almost all cells, while TNFR2 exhibits a limited expression, predominantly on regulatory T cells (Tregs). ...
Emerging evidence has demonstrated that TNFR1 is ubiquitously expressed on almost all cells, while TNFR2 exhibits a limited expressio …
Progress and prospect of mesenchymal stem cell-based therapy in atherosclerosis.
Zhang X, Huang F, Chen Y, Qian X, Zheng SG. Zhang X, et al. Am J Transl Res. 2016 Oct 15;8(10):4017-4024. eCollection 2016. Am J Transl Res. 2016. PMID: 27829989 Free PMC article. Review.
Research on atherosclerosis has shown that macrophage foam cell formation, inflammation, dyslipidemia and immune cells infiltration are all involved in regulating the onset and progression of atherosclerosis. Mesenchymal stem cells (MSCs) originated from diff …
Research on atherosclerosis has shown that macrophage foam cell formation, inflammation, dyslipidemia and immune cells infiltr …
Effects of myeloid and plasmacytoid dendritic cells on ILC2s in patients with allergic rhinitis.
Peng YQ, Qin ZL, Fang SB, Xu ZB, Zhang HY, Chen D, Liu Z, Bellanti JA, Zheng SG, Fu QL. Peng YQ, et al. J Allergy Clin Immunol. 2020 Mar;145(3):855-867.e8. doi: 10.1016/j.jaci.2019.11.029. Epub 2019 Dec 5. J Allergy Clin Immunol. 2020. PMID: 31812574 Free article.
BACKGROUND: Group 2 innate lymphoid cells (ILC2s) were reported to serve a critical role in allergic diseases. Myeloid dendritic cells (mDCs) and plasmacytoid DCs (pDCs) play significant roles in allergic immune response. ...
BACKGROUND: Group 2 innate lymphoid cells (ILC2s) were reported to serve a critical role in allergic diseases. Myeloid dendritic c
The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3.
Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, Gao Z, Tian H, Li Y, Yao Z, Zheng Y, Park BV, Pan Z, Zhang J, Dang E, Li Z, Wang H, Luo W, Li L, Semenza GL, Zheng SG, Loser K, Tsun A, Greene MI, Pardoll DM, Pan F, Li B. Chen Z, et al. Immunity. 2013 Aug 22;39(2):272-85. doi: 10.1016/j.immuni.2013.08.006. Immunity. 2013. PMID: 23973223 Free PMC article.
Regulatory T (Treg) cells suppress inflammatory immune responses and autoimmunity caused by self-reactive T cells. The key Treg cell transcription factor Foxp3 is downregulated during inflammation to allow for the acquisition of effector T cell-like fu …
Regulatory T (Treg) cells suppress inflammatory immune responses and autoimmunity caused by self-reactive T cells. The key Tre …
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